[Animal modeling] - Based on SDF-1/CXCR4 axis, observe the effect of Jisheng Shenqi Decoction on the homing of BMSCs in cirrhotic rats

To investigate the effect of Jisheng Shenqi Decoction on homing efficiency of bone marrow mesenchymal stem cells (BMSCs) through stromal cell-derived factor-1/CXC family chemokine receptor 4 axis, and analyze the mechanism of its combination with BMS...

2022-12-01

[Animal modeling] - Effects of long-term external or systematic application of glucocorticoid on the metabolic level and organs of mice

To observe the effects of long-term external or systematic use of glucocorticoid (GC) on the metabolic level and organs of normal mice...

2022-12-01

[Animal modeling] - Shenqi Pill reduces kidney damage in diabetes ZDF rats

To investigate the intervention effect of Shenqi Pill on renal injury in diabetes ZDF rats and whether its mechanism is to reduce ERS through PERK pathway...

2022-12-01

Animal tests show that the experimental universal vaccine can prevent known influenza strains

Science and Technology Daily News American scientists have developed an experimental universal influenza vaccine based on messenger ribonucleic acid (mRNA) molecules. In animal experiments, this vaccine can induce mice and ferrets to produce antibody...

2022-12-01

[Animal modeling] - Comparative study on three severe pancreatitis models of rats with different severity

To provide the basis for the researchers to select the appropriate concentration of sodium taurocholate to prepare SAP model of severe pancreatitis in rats...

2022-12-01

【Animal Modeling】-Screening of polymorphic microsatellite loci of guinea pig individuals and strains

To screen polymorphic microsatellite markers in guinea pigs and provide basic information for identifying the genetic structure and gene location of guinea pigs...

2022-11-30

【Animal Modeling】-Genetics of Guangxi cynomolgus monkeys using microsatellite DNA markers

To perform genetic testing on different production and breeding groups of cynomolgus monkeys in Guangxi, analyze the genetic background of cynomolgus monkeys in different breeding groups in Guangxi, and provide basic information for the establishment...

2022-11-30

【Animal modeling】-Protective effect of curcumin on renal fibrosis in 5/6 kidney ligation-induced chronic kidney disease mouse model

To study the protective effect of curcumin on renal fibrosis in chronic kidney disease, and to explore the possible mechanism of action...

2022-11-30

【Animal modeling】-Establishment of reference values of lymphocyte subsets in BALB/c mice, SD rats and cynomolgus monkeys

To collect the determination results of peripheral blood lymphocyte subsets completed by the National Center for Drug Safety Evaluation and Monitoring from 2007 to 2019 under the conditions of quality management of drug non-clinical research, and to...

2022-11-30

【Animal modeling】-Protective effect of aerobic exercise combined with paeonol PLGA nanoparticles on obese rats with hyperlipidemia

To investigate the effect of aerobic exercise combined with paeonol PLGA nanoparticles on blood biochemistry and lipid metabolism in obese rats with hyperlipidemia...

2022-11-30

【Animal modeling】-Based on the LIGHT/HVEM pathway to study the protective effect of resveratrol on renal injury in preeclamptic rats

To investigate the effect of resveratrol (RSV) on the lymphotoxin analog (LIGHT)/herpesvirus intervening body (HVEM) pathway in preeclampsia (PE) rats, and its protective effect on renal injury...

2022-11-29

Animal modeling] - camouflage technology inspired by cephalopod skin cells

A study found that combining a temperature-sensitive dye on a thin, flexible electrical substrate with a distributed light sensor could lead to systems that have the ability to automatically adapt to match the color of their surroundings, as a way fr...

2022-11-29

【Animal modeling】The effect of -13-methyltetradecanoic acid on abnormal oxygen in rat cerebral cortex astrocytes

To study the protective effect of 13-methyltetradecanoic acid on abnormal oxygen in rat cerebral cortical astrocytes...

2022-11-29

【Animal modeling】-Optimization of in vivo chromosomal aberration test in ICR mice

To conduct in vivo chromosomal aberration experiments in ICR mice, by administering cyclophosphamide and colchicine at different time points, to compare the effects of different administration/collection time points and different administration conce...

2022-11-29

【Animal Modeling】-Relationship between the expression of related splicing factors and the inclusion rate of SMN2 exon 7 in SMA mice

To study the inclusion of SMN2 exon 7 in different tissues of SMA mice, and to screen the related splicing factors...

2022-11-29

【Animal Modeling】-The effect of icariin on experimental IgA nephropathy in rats and related mechanisms

To explore the effects of different doses of icariin on rats with experimental IgA nephropathy, and to study its related mechanism...

2022-11-29