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![[Animal modeling - efficacy evaluation] - Vitamin D induced atherosclerosis model in rats](/./uploads/images/default/default.png)
Compared with the previous model of atherosclerosis induced by feeding animals with vitamin D, the one-time intraperitoneal injection of vitamin D has the advantages of simpler operation, lower cost, shorter time and higher success rate. This model h...
2024-09-19This model was created using primate macaques and fed a high-fat diet for 16-28 months. Compared with other animal models, its cardiovascular anatomy and physiological functions are closer to those of humans, but the modeling time is longer...
2024-09-19This model is modeled using quails, with a simple method and high modeling rate. But after 32-36 weeks of high-fat feeding and 4-6 weeks of basic feed feeding, the thickness of the aortic intima and plaque score were significantly reduced compared to...
2024-09-1920 healthy adult beagle dogs weighing 13-20kg; Reagent: Artificial seawater [Main indicators: osmotic pressure (1250 ± 11.52) mmol/L, pH 8.2, sodium ion (630 ± 5.33) mmol/L, potassium ion (10.88 ± 0.68) mmol/L, chloride ion (658.8 ± 5.25) mmol/L, sea...
2024-09-19After one week of adaptation in the model animals, right nephrectomy was performed. On the 7th day after surgery, a 2g/L solution of doxorubicin was injected into the tail vein at a dose of 5mg/kg. On the 30th day after surgery, doxorubicin was repea...
2024-09-19Root resorption is a common and difficult complication in orthodontic treatment. There are many factors that can cause root resorption, including age, gender, nutritional status, type of orthodontic appliance, magnitude of orthodontic force, orthod...
2024-09-18Implant restoration has been increasingly widely used in clinical practice, but tooth loss due to trauma, tumors, periodontal disease, and other reasons is often accompanied by excessive absorption of alveolar bone, resulting in insufficient bone mas...
2024-09-18There are 5 experimental miniature pigs in China, weighing 14-26kg, with 3 males and 2 females. Select the first permanent molars of the upper and lower jaws, and create a pulpitis model with bilateral mandibular incisors...
2024-09-18Guerreiro et al. established a model of myocardial hypertrophy in growing pigs using surgical methods...
2024-09-18Heart valve disease is an important disease that endangers human health, and the main treatment method is heart valve replacement surgery...
2024-09-18The changes in tongue coating and tongue texture are one of the main bases for clinical differentiation in traditional Chinese medicine. If similar changes to human tongue coating and tongue texture can be replicated in animal tongues, it will contri...
2024-09-18Adult male rats weighing 200-300g; Medications: Anesthetic, inulin, Escherichia coli lipopolysaccharide (LPS)...
2024-09-18Healthy adult rats, male and female not included; Medications: human blood, physiological saline, 50:50 alcohol and dry ice mixture, distilled water, potassium ferrocyanide, Dowex 50-8...
2024-09-18To investigate the effects of astragalus saponin Ⅱ on interleukin-21 (IL-21)/signal transducer and activator of transcription 3 (STAT3) pathway and airway inflammation in asthmatic young rats...
2024-09-14To observe the changes of intestinal flora in atherosclerosis model of Wuzhishan mini pig induced by high-fat and high-sugar diet...
2024-09-14To establish a reasonable and stable hyperuricemic renal damage mouse model, and provide a pathological model for screening and studying drugs for the treatment of hyperuricemic nephropathy...
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