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[Animal Modeling - Pharmacological Evaluation] - Lipopolysaccharide induced Brain Edema Model in Juvenile Mice

[Animal Modeling - Pharmacological Evaluation] - Lipopolysaccharide induced Brain Edema Model in Juvenile Mice

Animal: Healthy Wistar rats, weighing 70-100g, male or female not limited; Drug: Lipopolysaccharide...

2024-08-19
[Animal modeling - Drug efficacy evaluation] - pertussis bacterial solution induced cerebral edema model in rabbits

[Animal modeling - Drug efficacy evaluation] - pertussis bacterial solution induced cerebral edema model in rabbits

Animal: Healthy rabbit, weighing 1.75-2.15 kg; Medications: Anesthetics, pertussis bacterial fluid...

2024-08-19
[Animal Modeling Drug Efficacy Evaluation] - Typhimurium Lipopolysaccharide Induced Cerebral Edema Model in Rabbits

[Animal Modeling Drug Efficacy Evaluation] - Typhimurium Lipopolysaccharide Induced Cerebral Edema Model in Rabbits

rabbit; Medications: Anesthetic, typhoid lipopolysaccharide, 2.5% Evans blue saline solution; Equipment: Brain pressure gauge, multi-channel physiology instrument...

2024-08-19
[Animal Modeling - Pharmacological Evaluation] - Olive Oil Induced Cerebral Edema Model in Rabbits

[Animal Modeling - Pharmacological Evaluation] - Olive Oil Induced Cerebral Edema Model in Rabbits

rabbit; Medication: Anesthetic, olive oil, 2.5% Evans blue saline solution; Equipment: Brain pressure gauge, multi-channel physiology instrument...

2024-08-19
[Animal Modeling Drug Efficacy Evaluation]- Enterohemorrhagic Escherichia coli Mouse Infection Model

[Animal Modeling Drug Efficacy Evaluation]- Enterohemorrhagic Escherichia coli Mouse Infection Model

Normally, mice are not sensitive to wild-type EHEC O157: H7 infection. Adult mice of IQI, BALB/c, KM, and other strains are not susceptible to O157. Vaccination with live EHEC O157 EDL933W (NalR) at a dose of 10 ^ 10 to the power of 10 did not cause ...

2024-08-19
[Animal Modeling - Pharmacological Evaluation] - Sucrose Induced Hypertension Rat Model

[Animal Modeling - Pharmacological Evaluation] - Sucrose Induced Hypertension Rat Model

SD rats, weighing 142-180g; Drug: Sucrose...

2024-08-19
[Animal modeling - efficacy evaluation] - Preparation of non-human primate tuberculosis model

[Animal modeling - efficacy evaluation] - Preparation of non-human primate tuberculosis model

The non-human primate tuberculosis model is the closest animal model of tuberculosis to human tuberculosis...

2024-08-19
[Animal Modeling - Pharmacological Evaluation] - Adenosine induced Chronic Renal Failure in Rats with Hypertension Model

[Animal Modeling - Pharmacological Evaluation] - Adenosine induced Chronic Renal Failure in Rats with Hypertension Model

SD male rats weighing 150-190g; Drug: Adenosine, molecular weight 135.13...

2024-08-19
[Animal modeling - efficacy evaluation] - Preparation of tuberculosis free model

[Animal modeling - efficacy evaluation] - Preparation of tuberculosis free model

In the past, the preparation of rabbit tuberculosis models was mainly intravenous infection, but now aerosol infection is the most commonly used method...

2024-08-19
[Animal Modeling Drug Efficacy Evaluation] - HLA-B2704 Transgenic Mouse Spontaneous Anterior Uveitis Model

[Animal Modeling Drug Efficacy Evaluation] - HLA-B2704 Transgenic Mouse Spontaneous Anterior Uveitis Model

F1 generation was obtained by mating genetically modified positive mice, and F2 generation was obtained by mating sisters. The experimental animals include the first genetically modified mice, F1 and F2 generations...

2024-08-15
[Animal Modeling - Pharmacological Evaluation] - Natural Aging Animal Model of Heart Qi Deficiency Syndrome

[Animal Modeling - Pharmacological Evaluation] - Natural Aging Animal Model of Heart Qi Deficiency Syndrome

Experimental rats were raised for 18 months, and their general conditions such as activity, sleep, mental state, and fur were observed. Changes in body weight, ear temperature, exhaustion swimming time, respiratory rate, heart rate, and heart functio...

2024-08-15
[Animal Modeling Drug Efficacy Evaluation] - Elderly Dog Congestive Heart Failure Model

[Animal Modeling Drug Efficacy Evaluation] - Elderly Dog Congestive Heart Failure Model

Animal: Healthy aged Northwest hybrid dog, male, average age (8.6 ± 0.7) years, average weight (18.6 ± 2.5) kg...

2024-08-15
[Animal Modeling Drug Efficacy Evaluation] - Stellay type Interstitial Nephritis Model

[Animal Modeling Drug Efficacy Evaluation] - Stellay type Interstitial Nephritis Model

Male guinea pig, weighing 400-500g, New Zealand rabbit; Drug: Phosphate buffer solution (pH 7.1), complete Freund\'s adjuvant...

2024-08-15
【Animal modeling - Drug efficacy evaluation】 - Chronic serum nephritis

【Animal modeling - Drug efficacy evaluation】 - Chronic serum nephritis

rabbit; Drug: Bovine serum albumin (BSA)...

2024-08-12
[Animal Modeling - Pharmacological Evaluation] - Vibrio cholerae endotoxin induced uveitis model in rats

[Animal Modeling - Pharmacological Evaluation] - Vibrio cholerae endotoxin induced uveitis model in rats

Preparation of endotoxins: Vibrio cholerae 18001 strain, classical biotype, Ogawa serotype. ① The purified Vibrio cholerae species that have been identified will be first transferred from the inclined surface of the Houttuynia cordata to the Houttuyn...

2024-08-09
[Animal Modeling - Pharmacological Evaluation] - Bloodletting plus Propranolol Heart Qi Deficiency Animal Model

[Animal Modeling - Pharmacological Evaluation] - Bloodletting plus Propranolol Heart Qi Deficiency Animal Model

Adult rats were placed in a 30 ℃ environment for 1 hour, and their tails were cut 0.3-0.5cm and immersed in 37 ℃ warm water. Accurate quantification was performed using a graduated cylinder until 5ml of blood was lost, twice a day, for a total of 10 ...

2024-08-09