Language
OD mice are the best model for studying human type 1 diabetes, very similar to humans in genetics and immunology...
2021-03-12The middle-wavelength opsin cone dysfunction (MCD) rat in the retinal cone cells is a spontaneous gene mutation rat discovered by the Department of Aerospace Medicine, the Fourth Military Medical University, and is characterized by dark adaptation to...
2021-03-12Tumor necrosis factor-α (TNF-α) is mainly secreted by activated macrophages, and a small amount of activated T cells, NK cells and mast cells are also secreted...
2021-03-11The occurrence of lymphoma is a multi-factorial and multi-stage process. Various mechanisms such as cell cycle regulation, anti-apoptotic pathways, and tumor suppressor pathway abnormalities play an important role in the pathogenesis of lymphoma...
2021-03-11The most commonly used inducer is N-methylnitrosourea (MNU). Its carcinogenic mechanism is related to the formation of O6-methylguanine, resulting in GyA point mutations during DNA replication...
2021-03-11In the synthesis of thyroxine, the iodination reaction of thyroglobulin requires the catalysis of hydrogen peroxide and thyroid peroxidase. Dual oxidases (DUOX) provide hydrogen peroxide in this process. Mutations in the DUOX2 gene can cause hypothyr...
2021-03-11Type 2 diabetes is genetically inherited, and there are many mechanisms involved in the pathogenesis. In order to clarify the role of a single gene in the pathogenesis of type 2 diabetes, a series of type 2 diabetes animal models can be replicated by...
2021-03-11Animal model of diabetes induced by streptozotocin...
2021-03-11Spontaneously diabetic animals, also known as spontaneously hyperglycemic animals, are naturally occurring diabetes in animals, or a diabetes model preserved through genetic breeding. Its performance is very similar to the clinical symptoms of human ...
2021-03-11Intrauterine infection is one of the main causes of premature birth and premature infant diseases...
2021-03-11Perimenopausal period (perimenopausal period) refers to the period from the endocrine, biological and clinical features related to menopause appearing close to menopause to within one year of menopause, that is, the transition period of menopause to ...
2021-03-11In the early diagnosis and treatment of pancreatic cancer, it was found that the precancerous state of pancreatic cancer, that is, the molecular genetic abnormality of pancreatic duct epithelial tumors, is directly related to pancreatic cancer...
2021-03-10Introduce specific foreign genes into the genome of animals through genetic engineering methods, and integrate and replicate the genes to raise animals carrying the foreign genes...
2021-03-10Liver cancer model formed by transplanting liver cancer tissues, cell lines or other malignant tumors from animals or humans to animals...
2021-03-10The animal model of inducible liver cancer is a type of liver fiber that acts on experimental animals through chemical, physical and biological carcinogenic factors to induce the formation of animal liver cancer. The disease is a simulation of period...
2021-03-10By cutting the bile duct or injecting sclerosing agent, it will artificially block the extrahepatic bile duct, cause the bile duct to dilate, cholestasis, and increase the pressure in the bile duct above the blocked site....
2021-03-10