【Animal Modeling】-Therapeutic effect of anti-C5aR antibody combined with allicin on induced inflammatory bowel disease in rats

　　To explore the therapeutic effect of anti-complement 5a receptor (C5aR) antibody combined with allicin on inflammatory bowel disease (IBD) in rats...

2021-03-05

【Animal Modeling】-The effect of Huangqi injection on the mRNA expression of IL-1β, MCP-1 and TNF-α in the kidney of db/db mice

To explore the regulation effect of astragalus injection on immune cells and inflammatory factors in db/db mice and its possible mechanism...

2021-03-05

【Animal Modeling】-The effect and mechanism of rapamycin on myocardial injury after renal ischemia-reperfusion in rats

To explore the effect of rapamycin (RAPA) on the damage to the heart of distant organs after renal ischemia-reperfusion (RIR) in rats...

2021-03-04

【Animal Modeling】-Study on the anti-tumor effect of Xiuzhen mushroom powder on H22 tumor-bearing mice

To study the anti-tumor effect of Xiuzhen mushroom and its mechanism...

2021-03-04

【Animal Modeling】-The effect of hydroxychloroquine on the spleen lymphocytes of lupus mice

Observe the effect of hydroxychloroquine on the distribution of lymphocytes in the peripheral immune system (spleen) of mice with systemic lupus erythematosus (TC mice)...

2021-03-04

【Animal Modeling】-The protective effect of zedoary ketone on the cognitive function and nerve function of mice with cerebral ischemia-reperfusion injury

To explore the effects of zedoary ketone on the cognitive function, neurological function and mechanism of cerebral ischemia-reperfusion injury in mice...

2021-03-04

【Animal Modeling】-Effects of Different Exercise Mode Interventions on the Emotional Behavior of Aggressive Rats

To study the effects of various exercise interventions on the emotional behavior of aggressive rats...

2021-03-04

【Animal Modeling】-Preliminary study on serum cytokine expression profile of collagen-induced arthritis/syndrome model rats

To study the expression of serum cytokines in collagen-induced rheumatoid arthritis, cold-damp arthritis and damp-heat arthralgia/syndrome model rats...

2021-03-02

【Animal Modeling】-Using black-spotted double-finned electric rays to construct experimental autoimmune myasthenia gravis mouse model

How to establish an experimental autoimmune myasthenia gravis animal model that meets the international preclinical experimental standards?...

2021-03-02

【Animal Modeling】-Establishment and Evaluation of Rat Model of Chronic Fallopian Tube Inflammation of Qi Stagnation and Blood Stasis Type

Will we explore the method of establishing a chronic salpingitis model with stagnation and hyperemia, study its feasibility, conduct a preliminary evaluation of the model, and lay the foundation for further experimental research?...

2021-03-02

【Animal Modeling】-Establishment of a dual-target mouse model of myocardial ischemia and atherosclerotic plaque angiogenesis

Explore an effective method to establish a dual-target mouse model of myocardial ischemia and atherosclerotic plaque angiogenesis?...

2021-03-02

A mouse model of the brain\'s response to cold touch has been established and can be used to develop and test new therapies against colds and allergies

Neuroscientists at Carnegie Mellon University have used mouse models to map the sensation of cold touch to their brains...

2021-03-01

[Animal Modeling]-Urine Metabolome Study of Uyghur Medicine Abnormal Savda Rat Model

Do you want to combine the observation of external characteristics and the study of urine metabolomics to evaluate and discuss the biological markers in the rat model of Uyghur medical abnormal sava syndrome?...

2021-03-01

The effect of houttuyfonate sodium on the expression of PI3K, AKT1 and mTOR mRNA in the lung tissue of rats with chronic obstructive pulmonary disease

Observe the effect of sodium houttuyfonate on the expression of PI3K, AKT1 and mTOR mRNA in the lung tissue of rats with chronic obstructive pulmonary disease, and explore its mechanism of action...

2021-02-26

[Animal modeling]-Abnormal bone and mineral metabolism in adenine-induced chronic kidney disease rat model

Observe the characteristics of biochemical markers of mineral metabolism in adenine-induced chronic kidney disease (CKD) rat model? Vascular calcification and renal bone disease changes?...

2021-02-26

【Animal Modeling】-Establishment and evaluation of an animal model of premature ovarian failure induced by cyclophosphamide in rabbits

Compare different injection methods to establish animal models of primary ovarian insufficiency induced by cyclophosphamide, find the best modeling method, and provide a more suitable experimental model for further study of primary ovarian insufficie...

2021-02-26