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【Animal Modeling】-Comparison of rat models of fluorosis of different sexes

【Animal Modeling】-Comparison of rat models of fluorosis of different sexes

How to establish animal models of male and female fluorosis rats and study the gender differences in fluorosis?...

2021-02-26
[Animal modeling] 6-Hydroxydopa model rat salsolinol nitrogen methyltransferase activity detection

[Animal modeling] 6-Hydroxydopa model rat salsolinol nitrogen methyltransferase activity detection

Use 6-hydroxydopamine (6-OHDA) to establish a rat model of Parkinson\'s disease, and detect salsolinol nitrogen methyltransferase (SNMT) in peripheral blood lymphocytes of rats...

2021-02-26
【Animal Modeling】-Establishment and Evaluation of Rat Model of Endometriosis and Pelvic Adhesion

【Animal Modeling】-Establishment and Evaluation of Rat Model of Endometriosis and Pelvic Adhesion

To explore the method and evaluation index of establishing a rat model of endometriosis with pelvic adhesions...

2021-02-26
[Animal modeling]-Mouse model studies show that antidepressants may be used to treat multiple sclerosis

[Animal modeling]-Mouse model studies show that antidepressants may be used to treat multiple sclerosis

\"Nature Communications\" reported a systematic screening method for ordinary oral drugs, aimed at identifying drugs that are expected to be used to treat advanced multiple sclerosis...

2021-02-26
【Animal Modeling】-FTS and NIRF conjugated compound for imaging and treatment of mouse tumor models

【Animal Modeling】-FTS and NIRF conjugated compound for imaging and treatment of mouse tumor models

To study the targeting properties of farnesyl thiosalicylic acid (FTS) and heptamethylamine carbocyanine (Near-infrared, NIR) fluorescent dye binding compound and its application in in vivo imaging to clarify its effect on tumor growth Inhibitory eff...

2021-02-25
【Animal Modeling】-Establishment of a rat model of superior mesenteric vein thrombosis

【Animal Modeling】-Establishment of a rat model of superior mesenteric vein thrombosis

Use ligation to establish a rat model of superior mesenteric vein thrombosis, simulate the pathological process of the disease, and provide basic preparations for studying its pathogenesis and treatment methods...

2021-02-25
【Animal Modeling】-Establishment of mouse intermittent fasting model and its effect on glucose homeostasis

【Animal Modeling】-Establishment of mouse intermittent fasting model and its effect on glucose homeostasis

Study the stable, reliable alternatives to traditional calorie restriction in mouse models and their effects on blood glucose homeostasis...

2021-02-25
【Animal Modeling】-Research Progress of Experimental Animal Models of Diastolic Heart Failure

【Animal Modeling】-Research Progress of Experimental Animal Models of Diastolic Heart Failure

Diastolic heart failure, also known as heart failure with normal ejection fraction or heart failure with preserved ejection fraction, refers to patients with clinical symptoms and/or signs of heart failure, but lvef is normal or close to normal (lvef...

2021-02-25
【Animal Modeling】-The establishment and application of genetic modification tool pig model

【Animal Modeling】-The establishment and application of genetic modification tool pig model

Transgenic animals are animal strains obtained through artificial mutation...

2021-02-25
【Animal modeling】-Establishment and evaluation of a rat model of functional dyspepsia with spleen deficiency syndrome

【Animal modeling】-Establishment and evaluation of a rat model of functional dyspepsia with spleen deficiency syndrome

Explore the establishment and comparison of animal models of functional dyspepsia and spleen deficiency...

2021-02-25
[Animal modeling]-Telmisartan inhibits SOCS-3/SREBP-1c pathway to improve insulin resistance in rats with non-alcoholic steatohepatitis

[Animal modeling]-Telmisartan inhibits SOCS-3/SREBP-1c pathway to improve insulin resistance in rats with non-alcoholic steatohepatitis

To explore the inhibitory effect of telmisartan on the SOCS-3 pathway in the liver tissue of non-alcoholic steatohepatitis rats induced by high-fat diet and its intervention on insulin resistance...

2021-02-25
【Animal Modeling】-The resting energy metabolism rate is used to evaluate the role of glucocorticoids in kidney-yin deficiency and kidney-yang deficiency model

【Animal Modeling】-The resting energy metabolism rate is used to evaluate the role of glucocorticoids in kidney-yin deficiency and kidney-yang deficiency model

To observe the role of resting metabolic rate (RMR) in evaluating glucocorticoids for kidney-yin deficiency and kidney-yang deficiency syndrome models...

2021-02-25
【Animal Modeling】-Explore the correlation between the mouse model of chronic pelvic pain syndrome and the mechanical pain threshold and autophagy level

【Animal Modeling】-Explore the correlation between the mouse model of chronic pelvic pain syndrome and the mechanical pain threshold and autophagy level

Establish a C57BL/6 mouse model of chronic pelvic pain syndrome prostatitis and its mechanical pain threshold and the expression of autophagy-related microtubule light chain protein LC3 and substrate protein....

2021-02-25
Application of animal models in the preclinical study of mesenchymal stem cells in the treatment of chronic liver disease

Application of animal models in the preclinical study of mesenchymal stem cells in the treatment of chronic liver disease

Chronic liver disease is caused by liver damage factors such as viruses, autoimmunity, biliary atresia, toxins and metabolic disorders, and causes chronic liver disease...

2021-02-24
【Animal Modeling】-Establishing a mouse model of erlotinib-induced skin adverse reactions

【Animal Modeling】-Establishing a mouse model of erlotinib-induced skin adverse reactions

Erlotinib is a new target drug for the treatment of non-small cell lung cancer. It has been widely used clinically in recent years, but it has many side effects...

2021-02-24
Establishment of Coxsackie Virus Type A16 Infection Model and Evaluation of Related Immunological Indexes and Application

Establishment of Coxsackie Virus Type A16 Infection Model and Evaluation of Related Immunological Indexes and Application

Establish a simple and reliable small rodent experimental animal model sensitive to Coxsackie virus A16 (CVA16)...

2021-02-24