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![[Disease animal model]-Myocardial ischemia and myocardial infarction animal model](/./uploads/images/default/default.png)
Methods to replicate animal myocardial ischemia and myocardial infarction models include ligation of coronary arteries and some left circumflex coronary arteries, most of which ligate the anterior descending branch of the left coronary artery...
2021-03-09Arrhythmia can be reproduced in the whole animal, or perfused in vitro by in vitro perfusion of the isolated heart or specific parts of the heart, depending on various experimental purposes...
2021-03-09High-cholesterol and high-fat feed method: At present, it is a more commonly used method, which has the characteristics of low mortality and long-term observation, but it is time-consuming. Usually, rabbits, pigeons, chickens, etc. can cause obvious ...
2021-03-09Whole gene knockout is to replace the target gene with a foreign DNA sequence (in most cases, the neomycin resistance gene used for drug screening), so as to achieve the purpose of inactivating the target gene...
2021-03-08Mice were randomly divided into normal saline control group, high, medium, and low infection dose groups according to their body weight. Each group was 10 mice and were inoculated with 1×108, 1×107 or 1×106 TCID50 virus to observe clinical symptoms a...
2021-03-08Altitude sickness (called \"altitude sickness\") is a chronic altitude sickness caused by excessive red blood cell proliferation (excessive red blood cell proliferation) caused by high altitude hypoxia...
2021-03-08Extraction and identification of bovine sciatic nerve myelin basic protein (MBP) ① Extraction of MBP: modified according to London method...
2021-03-08Rats, guinea pigs and monkeys that inhale irritating gases (sulfur dioxide, chlorine, ammonia, smoke, etc.) are often selected to replicate chronic bronchitis in humans...
2021-03-08Parkinson’s disease is the world’s second largest neurodegenerative disease after Alzheimer’s, posing a serious threat to the health of middle-aged and elderly people...
2021-03-08Coxsackie virus A16 (CA16) is generally considered to be one of the main pathogens of human hand, foot and mouth disease. The clinical manifestations of hand, foot and mouth disease include small vesicles on the hands, feet and mouth, as well as seve...
2021-03-08Arrhythmia can be reproduced in the whole animal, or in vitro perfused through the isolated heart or specific parts of the heart, depending on various experimental purposes...
2021-03-08Animal models of pancreatitis are the best way to study the causes of pancreatitis and explore clinical treatments, but the cause of pancreatitis is still unknown, and there is no good method, because the cause varies with the type of pancreatitis...
2021-03-08The 16th autosomal recessive mutation (SCID) of the mouse is a mutant mouse 1. The homozygous SCID mouse gene almost completely loses the function of mouse T and B lymphocytes, and has been widely used in this type of mouse. In immunology and oncol...
2021-03-08Amphibians such as frogs and toads have the same basic life activities and physiological functions as warm-blooded animals, and can easily understand the living conditions of isolated tissues...
2021-03-08Rats and mice can be said to be stars in life science laboratories. Successful rat and mouse models can be said to be \"excellent assistants in life sciences.\" Many people may want to design or understand conditional knockout mice....
2021-03-08In order to simulate human Parkinson\'s disease, an ideal animal model should have the following characteristics: (1) The number and morphology of dopaminergic neurons at birth are normal, and they gradually decrease selectively during adolescence, r...
2021-03-08