【Animal Modeling】-Shenyi capsule combined with 5-fluorouracil inhibits angiogenesis of colon cancer in mice

Explore the inhibitory effect of Shenchang Capsule combined with 5-fluorouracil (5-fluorouracil, 5-FU) on colon cancer growth and angiogenesis and its possible mechanism?...

2021-02-03

【Animal Modeling】-Aspirin\'s Mechanism of Controlling Salt Sensitive Hypertension in Rats

Explore the regulatory effect of aspirin on salt-sensitive hypertensive rats and related mechanisms?...

2021-02-03

【Animal Modeling】-The effect of maca combined with exercise therapy on the activity of respiratory chain enzymes and renal function of diabetic rats

To observe the effect of maca combined with exercise therapy on the activity of renal mitochondrial respiratory enzymes and renal function in diabetic rats...

2021-02-03

【Animal Modeling】-The Intervention Effect and Mechanism of Low Molecular Heparin Calcium on Mouse Embryo Implantation

To explore the interventional effect and mechanism of low molecular weight heparin calcium on mouse embryo implantation...

2021-02-03

[Animal Modeling]-Abnormal glucose metabolism leads to the acute weight change of SIVmac239 infected Beiping-topped monkey

How to study the influence of inflammatory factors, lipid metabolism and glucose metabolism on body weight in the acute phase of AIDS?...

2021-02-03

【Animal Modeling】-The effect of warming spleen and kidney method on chemokine signaling pathway in colon tissue of UC rats with spleen and kidney yang deficiency

How to find the specific target of spleen, kidney and renal insufficiency?...

2021-02-03

【Animal Modeling】-Emodin\'s effect on fat browning in ApoE knockout mice

Would you like to observe the effect of emodin on fat browning in apolipoprotein knockout (ApoE-/-) mice, and explore the mechanism of improving congestion such as hyperlipidemia?...

2021-02-03

【Animal Modeling】-Object Cognition--Research on a Learning and Memory Evaluation Method Based on the Spontaneous Behavior of Animals

Research object recognition experiment, object recognition experiment, object position recognition experiment, time memory experiment and episodic memory experiment four models of experimental procedures and evaluation indicators, and study learning ...

2021-02-02

【Animal Modeling】-The role of nerve growth factor antibody in mouse knee osteoarthritis pain model

Knee osteoarthritis (OA) is a common chronic degenerative disease characterized by degeneration of articular cartilage components, synovitis, subchondral bone remodeling and joint muscle atrophy...

2021-02-02

[Animal modeling]-Optimization of the dose-effect relationship between N-ethyl-N-nitrosourea and cyclophosphamide in the Pig-a gene mutation test in rats

To study the effect of different doses of N-ethyl-N-nitrosourea (ENU) and cyclophosphamide (CP) on the deletion rate of ankyrin CD59 on the peripheral red blood cell surface of SD rats, and optimize the detection method of Pig-a gene mutation test...

2021-02-02

[Animal Modeling]-The damage effect of Busulfan on the function of hematopoietic stem cells in mice

Explore the effects of various administration methods on the function of hematopoietic stem cells in mice...

2021-02-02

【Animal Modeling】-The effect of vitamin D deficiency on the pathogenesis of spontaneous diabetic rats

To explore the effect of vitamin D deficiency on the etiology of spontaneous diabetic rats...

2021-02-02

[Animal Modeling] The effect of botulinum toxin type A heavy chain intervention on the expression of growth-related proteins after spinal cord injury in rats

To explore the effect of artificially recombined botulinum toxin type A heavy chain (BoNT/A heavy chain) on the expression of local growth-related proteins in rats with spinal cord injury, and provide a basis for elucidating its mechanism...

2021-02-02

【Animal Modeling】-The effect of high-fat feed feeding time on type 2 diabetic nephropathy rat model

How to investigate the effect of feeding time on the blood glucose, insulin resistance index (HOMA-IR) and urinary albumin excretion rate (UAER) of a variety of high-fat diets in type 2 diabetic nephropathy rat models?...

2021-02-02

Effect of Inhibiting Peripheral Neuron PAR2-PKA/PKCε Pathway on Pain Threshold in Rats with Pain Transformation Model

To explore the role of peripheral neuroprotease activated receptor 2-protein kinase A/protein kinase Cε (PAR2-PKA/PKCε) pathway in pain changes, and possible solutions for simultaneous intervention in acute and chronic pain...

2021-02-02

Cysteinyl leukotriene receptor antagonist reduces global cerebral ischemia-reperfusion injury in Mongolian gerbils by down-regulating autophagy

To explore the protective effect and mechanism of cysteinyl leukotriene receptor antagonists (Plukast, HAMI 3379) on global cerebral ischemia-reperfusion injury in Mongolian gerbils...

2021-02-02