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Scientists have developed a new method to generate hematopoietic stem cells with continuous energy

Scientists have developed a new method to generate hematopoietic stem cells with continuous energy

Recently, in a research report published in the international journal Cell Reports, scientists from the Spanish Genome Regulatory Center and Columbia University have identified a special kind that is essential for the expansion of scarce and life-sav...

2021-02-17
Hematopoietic stem cells improve immune response by maintaining memory of previous infections

Hematopoietic stem cells improve immune response by maintaining memory of previous infections

In a new study, researchers from France, Germany, and Israel discovered a surprising property of hematopoietic stem cells: They not only ensure the continuous renewal of blood cells, but also remember the previous infection experience, which will tri...

2021-02-17
Heavy! Scientists have developed a new strategy that can promote healthier hematopoietic stem cells!

Heavy! Scientists have developed a new strategy that can promote healthier hematopoietic stem cells!

Hematopoietic stem cells (HSCs) located in the bone marrow can produce all the blood cells of the body, including key immune cells that can protect the body against bacterial and viral infections. As the body ages, HSCs will become no longer effectiv...

2021-02-17
MAIT cell activation enhances the immunogenicity of adenovirus vector vaccine

MAIT cell activation enhances the immunogenicity of adenovirus vector vaccine

Mucosal-associated invariant T cell (Mucosal-associated invariant T cell, MAIT) is a subgroup of T cells that is important for mucosal homeostasis...

2021-02-16
Reveal that the protein NRLP1 specifically recognizes double-stranded RNA to detect the mechanism of viral infection

Reveal that the protein NRLP1 specifically recognizes double-stranded RNA to detect the mechanism of viral infection

In a new study, Veit Hornung of the University of Munich, Germany, and his team confirmed that a protein called NRLP1 found in skin cells can recognize specific nucleic acid intermediates formed during virus replication...

2021-02-16
New research maps the development of inhibitory neuronal circuits in the cerebral cortex

New research maps the development of inhibitory neuronal circuits in the cerebral cortex

How to build a neural network that is more complex than anything currently known? In a new study, researchers from the Max Planck Institute for Brain Research in Germany mapped out the developmental map of inhibitory neuronal circuits and reported th...

2021-02-16
The relationship between oral disease and COVID19

The relationship between oral disease and COVID19

According to a study published in the Journal of Clinical Periodontology of the European Federation of Periodontics (EFP), if patients with COVID-19 also have gum disease, they are at least three times more likely to develop complications...

2021-02-15
Chronic SARS-CoV-2 infection can cause mutations

Chronic SARS-CoV-2 infection can cause mutations

Recently, a team led by Cambridge researchers published an article in the journal Nature, reporting how they observed SARS-CoV-2 mutations in immunocompromised patients receiving restorative plasma therapy...

2021-02-15
HBV

HBV

Currently, about 260 million people (more than 3% of the global population) are chronically infected with hepatitis B virus (HBV)...

2021-02-15
Hydroxychloroquine does not help patients with COVID-19

Hydroxychloroquine does not help patients with COVID-19

According to an article recently published in the Cochrane Review, hydroxychloroquine cannot reduce COVID-19 deaths, and may not reduce the number of people who need ventilators....

2021-02-14
Two gene therapies can cure rare genetic diseases!

Two gene therapies can cure rare genetic diseases!

Arginase deficiency is a rare genetic disease that causes the accumulation of the amino acid arginine in the blood...

2021-02-11
Gene characteristics of placental membrane cells determine the chance of preterm birth

Gene characteristics of placental membrane cells determine the chance of preterm birth

In a recent study, the Dimes Preterm Birth Research Center, led by researchers from the University of Chicago, conducted a new study that found new genetic markers related to gestational age and provided new insights into potential risk factors for p...

2021-02-10
CRISPR-Cas9 technology can effectively treat sickle cell anemia and β-thalassemia

CRISPR-Cas9 technology can effectively treat sickle cell anemia and β-thalassemia

Sickle cell anemia (SCD) and β-thalassemia (TDT) are two common gene-deficient diseases. The common feature is that the globin gene defect causes the synthesis of one or more of the globin peptide chains in hemoglobin to decrease Or cannot be synthes...

2021-02-10
Research reveals a neurological disease similar to Parkinson\'s

Research reveals a neurological disease similar to Parkinson\'s

A collaborative study between the National Institute of Neuroscience (NNI) and Singapore General Hospital (SGH) shows that patients diagnosed with Parkinson’s disease may actually have NIID...

2021-02-10
Gene therapy PBGM01 was approved by EMA orphan drug for the treatment of GM1 gangliosidosis

Gene therapy PBGM01 was approved by EMA orphan drug for the treatment of GM1 gangliosidosis

Focusing on the development of single gene conversion therapy for rare central nervous system diseases, the European Commission (EC) has led the treatment of GM1 gangliosidosis in the company on the 26th...

2021-02-10
[Animal modeling]-Observation of the effect of thrombopoietin on cardiomyocyte apoptosis in rats with adriamycin-induced heart failure based on the TGF-β1/Smad3 signaling pathway

[Animal modeling]-Observation of the effect of thrombopoietin on cardiomyocyte apoptosis in rats with adriamycin-induced heart failure based on the TGF-β1/Smad3 signaling pathway

To explore the effect of thrombopoietin (TPO) on adriamycin-induced heart failure (CHF) rat cardiomyocyte apoptosis and its regulatory mechanism on TGF-β1/Smad3 signal...

2021-02-07