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Compound Zhenzhu Tiaozhi Capsule Regulates MEKK2-Wnt Coupling and Antagonizes β-catenin Ubiquitination Improves Glucocorticoid Osteoporosis in Rats

Compound Zhenzhu Tiaozhi Capsule Regulates MEKK2-Wnt Coupling and Antagonizes β-catenin Ubiquitination Improves Glucocorticoid Osteoporosis in Rats

  Through the intervention of Zhenzhu Tiaozhi Capsule (FTZ), a compound that antagonizes β-catenin ubiquitination and bone and cell changes, explore the regulation of mitogen-activated protein kinase 2-Wnt...

2021-02-02
[Animal Modeling]-Correlation between cognitive development and hippocampal dopamine and dihydroxyphenylacetic acid in 80-day-old pups from pregnant rats

[Animal Modeling]-Correlation between cognitive development and hippocampal dopamine and dihydroxyphenylacetic acid in 80-day-old pups from pregnant rats

  To investigate the effects of cognitive development and dopamine (DA) and dopamine (3,4-dihydroxyphenylacetic acid, DOPAC) levels in hippocampus of 80-day-old pups born from pregnant rats with fear of injury, and explore the correlation between the...

2021-02-01
【Animal Modeling】-Curcumin\'s chemical intervention effect and mechanism analysis on N-methylnitrosourea-induced bladder cancer in rats

【Animal Modeling】-Curcumin\'s chemical intervention effect and mechanism analysis on N-methylnitrosourea-induced bladder cancer in rats

To analyze the chemical intervention and mechanism of curcumin in the rat model of bladder cancer induced by N-methylnitrosourea (MNU)...

2021-02-01
[Animal Modeling]-Metabonomics study of changes in metabolic pathways during the immunosuppressive effect of cyclophosphamide on mice

[Animal Modeling]-Metabonomics study of changes in metabolic pathways during the immunosuppressive effect of cyclophosphamide on mice

Using metabonomics method to study the changes of metabolic pathways during the immunosuppressive effect of cyclophosphamide on mice...

2021-02-01
【Animal Modeling】-Analysis of Right Heart Function in Rats with Alkaline Pulmonary Hypertension

【Animal Modeling】-Analysis of Right Heart Function in Rats with Alkaline Pulmonary Hypertension

Study the relationship between changes in pulmonary artery pressure and changes in right ventricular function...

2021-02-01
【Animal Modeling】-The effect of PM2.5 on rat uterine tissue morphology and oxidative stress

【Animal Modeling】-The effect of PM2.5 on rat uterine tissue morphology and oxidative stress

To explore the effects of PM2.5 on the physiology and related biochemical stress of rat uterine tissue...

2021-02-01
【Animal Modeling】The effect of -20Hz square wave and sine wave frequency flash on the eyeball development of guinea pigs

【Animal Modeling】The effect of -20Hz square wave and sine wave frequency flash on the eyeball development of guinea pigs

To evaluate the effects of continuous high frequency sine wave and square wave stroboscopic on emmetropia and eye development in guinea pigs...

2021-02-01
【Animal Modeling】-The effect of miR-424 on the migration and invasion of non-small cell lung cancer cell line A549

【Animal Modeling】-The effect of miR-424 on the migration and invasion of non-small cell lung cancer cell line A549

To investigate the effect of miR-424 on the migration and infiltration of non-small cell lung cancer A549 cells...

2021-02-01
【Animal Modeling】-Mice experiments reveal that gene therapy is expected to restore eyesight to patients

【Animal Modeling】-Mice experiments reveal that gene therapy is expected to restore eyesight to patients

Researchers at the University of Oxford in the United Kingdom reported recently that their newly developed gene therapy can regain the sight of blind mice. This method is expected to be used to treat eye diseases such as human retinitis pigmentosa...

2021-02-01
【Animal Modeling】-The influence of air sac on the results of abdominal wall withdrawal reflex experiment

【Animal Modeling】-The influence of air sac on the results of abdominal wall withdrawal reflex experiment

To select suitable materials to prepare balloons for abdominal wall retraction reflex experiments...

2021-02-01
【Animal Modeling】-Comparison of ulcer wound healing in two type 2 diabetic mice

【Animal Modeling】-Comparison of ulcer wound healing in two type 2 diabetic mice

Comparing C57BL/6J-db/db and STZ-induced ulcer healing properties in C57BL/6J mice, these mice have spontaneous mutations of commonly used genes in type 2 diabetic mice with stable diabetes, providing a basis for establishing mouse ulcer models. Rela...

2021-02-01
【Animal Modeling】-The effect of sugar supplementation on the activation of myocardial adenosine monophosphate activated protein kinase in acute exercise rats

【Animal Modeling】-The effect of sugar supplementation on the activation of myocardial adenosine monophosphate activated protein kinase in acute exercise rats

  By measuring the changes of AMP-activated protein kinase (AMPK) activity and glycogen content in rats after acute exercise, the effect of supplementing glucose on the activation of AMPK in exercise myocardium is explored...

2021-02-01
[Animal Modeling]-Proliferation of Umbilical Cord Mesenchymal Stem Cells on Dairy Cow Mammary Epithelial Cells under Serum-Free Co-culture Conditions

[Animal Modeling]-Proliferation of Umbilical Cord Mesenchymal Stem Cells on Dairy Cow Mammary Epithelial Cells under Serum-Free Co-culture Conditions

To study the proliferation of umbilical cord mesenchymal stem cells (UC-MSC) in bovine mammary epithelial cells (BMEC) under serum-free co-culture conditions...

2021-02-01
【Animal Modeling】-Expression and purification of Asprosin and its effect on mouse heart function in vivo

【Animal Modeling】-Expression and purification of Asprosin and its effect on mouse heart function in vivo

Study the effect of E. coli prokaryotic expression and purification of proprosin protein on improving heart function...

2021-02-01
【Animal Modeling】-The protective effect of nimodipine on PC12 cell apoptosis induced by H2O2

【Animal Modeling】-The protective effect of nimodipine on PC12 cell apoptosis induced by H2O2

To explore the protective effect of nimodipine on the apoptosis of PC12 cells induced by hydrogen peroxide (H2O2)...

2021-01-29
【Animal Modeling】-The effect of microinjection of K252a into the hippocampus on rat behavior and depression-like classic indicators

【Animal Modeling】-The effect of microinjection of K252a into the hippocampus on rat behavior and depression-like classic indicators

K252a was microinjected into the hippocampus to study its effect on rat behavior and classic depression-like indicators to establish a new type of depression animal model...

2021-01-29