[Animal modeling] - Chinese hamster with primary diabetes

About 10 strains of Chinese hamster diabetes model animals have been cultivated (such as inbred Chinese hamster cultivated by the Experimental Animal Center of Shanxi Medical University), some of which are severe diabetes with ketosis, some are diabe...

2024-07-05

[Animal modeling] Establishment and evaluation of an animal model of Alzheimer\\

To explore and establish a reliable animal model of Alzheimer\\\'s disease combined with phlegm and blood stasis syndrome, and to provide the corresponding animal model for the prevention and treatment of AD by traditional Chinese medicine and provid...

2024-07-05

【Animal modeling】-Effect of vitamin D deficiency on the pathogenesis of spontaneously diabetic rats

To investigate the effect of vitamin D (VD) deficiency on the pathogenesis of spontaneous diabetic rats...

2024-07-04

【Animal Modeling】-Effects of intermedia and adrenomedullin on cerebral microcirculation in rats with focal cerebral ischemia

To investigate the effects of intermedin and adrenomedullin on cerebral microcirculation in rats with focal cerebral ischemia...

2024-07-04

[Animal Modeling Pharmacodynamic Evaluation] - Establishment of Vascular Dementia Animal Model by Cerebrovascular Embolism Method

Take sterile and naturally dried blood clots of the same type of rat, grind them and pass them through a 200 μ m sieve for later use. When using, 0.5ml of physiological saline was taken and 100mg of blood clot was homogenized to form a suspension. Th...

2024-07-04

[Animal modeling] Effects of 8-week aerobic exercise on skeletal muscle inflammation and exercise capacity in obese mice

To explore the effect of 8-week aerobic exercise on obesity induced by high-fat diet in mice...

2024-07-04

【Animal modeling - Pharmacodynamic evaluation】 - Establishment of vascular dementia animal model using cerebral ischemia method

　　Preoperative fasting of water for 12 hours. After intraperitoneal injection of 10% Ulartan (1g/kg) anesthesia, disinfection was performed, and a blunt separation of bilateral common carotid arteries and nerves was made through a midline incision. T...

2024-07-04

【Animal Modeling】-Comparison of the ability of rat adipose stem cells and bone marrow mesenchymal stem cells to differentiate into endothelial cells

To study the ability of adipose stem cells (ASCs) to differentiate into endothelial cells and compare with bone marrow mesenchymal stem cells (BMSCs)...

2024-07-03

[Animal modeling] - Based on the rat OVX model, study the effect of estrogen deficiency on the degeneration of endplate chondrocytes

To investigate the effect of estrogen deficiency on the degeneration of endplate chondrocytes...

2024-07-03

【Animal Modeling】-Effects of Four Commonly Used Experimental Anesthetics on Cardiovascular System of Rats

To investigate the effects of different animal experimental anesthetics on the cardiovascular system of rats...

2024-07-03

[Animal modeling - Pharmacodynamic evaluation] - Establishment of vascular dementia animal model using cerebral ischemia method

Fasting water for 12 hours before surgery. After intraperitoneal injection of 10% Ulartan (1g/kg) anesthesia, disinfection was performed, and a median cervical incision was made. Bilateral common carotid arteries (CCA) and nerves were bluntly separat...

2024-07-02

[Animal Modeling Pharmacodynamic Evaluation] - Tear Deficiency Rabbit Dry Eye Model

Surgical removal of lacrimal gland, Harder\'s gland, and creation of a tear deficient rabbit dry eye model with the third eyelid...

2024-07-02

Animal Modeling Pharmacodynamic Evaluation Pituitrin Induced Myocardial Ischemia Model

Rats were intravenously injected with 0.5u/kg or 11u/kg of pituitrin, with a volume of 1 or 1.5ml, and the injection was completed within 10 or 15 seconds...

2024-07-02

[Animal modeling - efficacy evaluation] - Preparation of diabetes cardiomyopathy model

The rats were fed with a high sugar and high fat diet (10% lard, 20% sucrose, 2% cholesterol, 1% sodium cholate, 67% conventional diet) for 4 weeks, and venous blood was collected for fasting (fasting for 10 to 12 hours, during which free drinking wa...

2024-07-02

[Animal modeling - Pharmacodynamic evaluation] - Coronary artery balloon induced myocardial ischemia model

After anesthesia, the animal undergoes artificial respiration. After thoracotomy from the 4th or 5th intercostal space, the anterior descending branch of the left coronary artery is separated by about 1cm (or a segment of the left circumflex branch) ...

2024-07-02

[Animal modeling - Pharmacodynamic evaluation]- Animal model of fecal roundworm infection

The fecal roundworm is the only worm that has both a complete free living generation and a parasitic generation...

2024-07-02