[Animal Modeling - Pharmacological Evaluation] - Acute Gastritis Animal Model

Adult male rats were fasted without water for 48 hours, orally administered with 100mg/kg body weight of acetylsalicylic acid, or 10mmol/L acetic acid or different concentrations of hydrochloric acid (1, 10, 10mmol/L), or administered with the same b...

2024-08-26

[Animal modeling - Drug efficacy evaluation] - Acid infusion method for reflux esophagitis model

Apply adult rabbits weighing 2-3kg. Rabbits were fasted for 12 hours before surgery but were unable to drink water...

2024-08-26

[Animal Modeling Drug Efficacy Evaluation] - Esophageal Varicose Vein Model of Canine Portal Hypertension

Adult Beagle dogs were fasted 16 days before surgery and anesthetized with 10mg/kg body weight of ketamine via intramuscular injection. The animals were then placed on the operating table for fixation...

2024-08-26

[Animal Modeling Drug Efficacy Evaluation] - Esophageal Narrowing Animal Model

Adult Beagle dogs weighing 8-14kg were anesthetized by intravenous injection of pentobarbital sodium at a dose of 30mg/kg body weight. The dogs were then fixed on their side on the operating table, and the neck surgical area was routinely disinfected...

2024-08-26

[Animal Modeling - Efficacy Evaluation] - Extracorporeal Circulation Animal Model

　　Rats were anesthetized by intraperitoneal injection of pentobarbital sodium at a dose of 30mg/kg body weight, followed by oral intubation and mechanical ventilation (frequency 60 times/min, peak airway pressure 9.0cmH2O (0.88kPa)). Left femoral art...

2024-08-26

[Animal Modeling - Pharmacological Evaluation] - Portal Hypertension Esophageal Varicocele Animal Model

After fasting and water deprivation for 8 hours, rats were anesthetized using conventional methods and fixed in a supine position on the operating table. The skin was cut 2.5-3.0cm in the center of the abdomen, and the abdominal cavity was opened alo...

2024-08-26

[Animal Modeling - Pharmacological Evaluation] - Saffron Red O-induced Kidney Disease Model in Rabbits

rabbits, weighing 2-3kg; Medication: Saffron Red O, Renluo Liquid...

2024-08-26

[Animal modeling - Drug efficacy evaluation] - Purimycin induced nephropathy model

Healthy male rats weighing 100-150g; Drug: Puromycin...

2024-08-26

【Animal Modeling - Pharmacological Evaluation】 - Lead induced Nephropathy Animal Model

Healthy male SD rats, weighing (220 ± 20) g; Drug: Lead acetate...

2024-08-26

[Animal Modeling - Pharmacological Evaluation ]- Chemical induced Pulmonary Edema Animal Model

Adult New Zealand rabbits weighing over 2kg were anesthetized with pentobarbital sodium injected intraperitoneally at a dose of 30mg/kg body weight, and then placed supine with their head and limbs fixed on the operating table. Neck hair removal, rou...

2024-08-22

[Animal Modeling - Pharmacological Evaluation] - Respiratory Distress Syndrome Animal Model

Administer a dose of 120mg/kg body weight to experimental rats by gavage, diluted with physiological saline to 20mg/L paraquat...

2024-08-22

[Animal Modeling - Pharmacological Evaluation] - Bronchiectasis Animal Model

SD rats weighing around 200g and around 4 months old were anesthetized by intraperitoneal injection of pentobarbital sodium at a dose of 30mg/kg body weight. The animal is fixed in a supine position on the surgical plate. After routine disinfection a...

2024-08-22

[Animal Modeling - Pharmacological Evaluation] - Transgenic Animal Model of Bronchial Asthma

Mainly using transgenic or gene knockout technology to study the role of changes in certain gene expression products in the development of asthma...

2024-08-22

[Animal Modeling - Efficacy Evaluation] - Abdominal Infection Model of Canine Intraperitoneal Injection of Fecal Filtrate

Anesthetize adult healthy dogs by intraperitoneal injection of pentobarbital sodium at a dose of 40mg/kg body weight; After anesthesia, the animal is fixed supine on the surgical plate, and the abdominal surgical area is routinely disinfected. The ab...

2024-08-22

[Animal Modeling - Pharmacological Evaluation] - Rat Intestinal Fistula Surgery Abdominal Infection Model

Use male adult rats weighing 250-270g. Abdominal infection group underwent intestinal fistula surgery: Rats were fasted for 8 hours before surgery, anesthetized with ketamine injected intraperitoneally at a dose of 100mg/kg body weight, and then fixe...

2024-08-22

[Animal Modeling - Pharmacological Evaluation] - Septicemia Mouse Animal Model

BALB/c mice weighing 21-25g (rats weighing around 200g can also be used), regardless of gender. Animals were raised adaptively for one week and fasted for 12 hours before the experiment. After intraperitoneal injection of pentobarbital sodium anesthe...

2024-08-22