[Animal modeling - Drug efficacy evaluation]- Electrical stimulation induced myocardial ischemia model

male rabbit; Instrument: Electrical Stimulator...

2024-08-07

Animal Modeling - Pharmacological Evaluation - Tear Deficiency Mouse Dry Eye Model

New Zealand black/white (NZB/NZW) F1 hybrid mice obtained by hybridization technology can produce significant autoimmune reactions in their lacrimal gland tissue with age, exhibiting changes similar to Sj ö gren\'s syndrome...

2024-08-07

[Animal Modeling - Pharmacological Evaluation] - Chronic Compression Sciatic Nerve Injury Model

SD rats, female, 180-250g; Drug: Anesthetic...

2024-08-07

[Animal Modeling - Pharmacological Evaluation]- Cat Chronic Optic Nerve Injury Model

Adult healthy domestic cats, male or female, weighing 2.5-3.5kg; Drug: Anesthetic; Equipment: Experimental balloon...

2024-08-07

[Animal Modeling Drug Efficacy Evaluation] - Rat Trigeminal Neuralgia Model

SD rats, weighing 250-300g, male or female not limited; Drug: 5% formaldehyde...

2024-08-07

[Animal Modeling - Efficacy Evaluation] - Genetic Cataract Animal Model

In clinical practice, partial or complete opacity of the crystalline lens that exists or gradually forms after birth is called congenital cataract...

2024-08-07

[Animal Modeling Drug Efficacy Evaluation ]-Brain Spinal Cord Inflammation Model

Modeling material animal: guinea pig, weighing around 400g, male or female not limited; Drug: Freund adjuvant, physiological saline; apparatus...

2024-08-07

[Animal Modeling - Efficacy Evaluation] - Age Related Cataract Animal Model

Macaques and humans are both higher animals belonging to the primate order. The anatomy and physiology of their eyes are very similar to those of humans. The normal crystalline lens of macaques is also colorless and transparent, with a biconvex lens ...

2024-08-07

[Animal Modeling Drug Efficacy Evaluation] - Spontaneous Animal Tumor Model

A type of tumor that naturally occurs in experimental animal populations without conscious artificial experimental treatment is called spontaneous tumor...

2024-08-07

[Animal modeling - efficacy evaluation] - transgenic diabetes animal model

Bruning et al. introduced ineffective alleles of insulin receptor (IR) and insulin receptor substrate 1 (IRS-1) into mice through double heterozygosity, resulting in a decrease in IR/IRS-1 expression in the mice...

2024-08-07

[Animal Modeling - Pharmacological Evaluation] - Evaporation induced Mouse Dry Eye Model

Dysfunction of meibomian gland and strong evaporation type rabbit dry eye model. Some special types of mice already have factors of meibomian gland developmental disorders...

2024-08-07

[Animal modeling - efficacy evaluation] - DB/DB obese diabetes mice

Diabetes mice: It was first reported by Hummel et al. (1966) that it was caused by a recessive mutation gene and spontaneously originated from inbred mice (C57BL/Ks) in Jackson\'s laboratory. This gene (db) and obesity (ob) are not alleles, but locat...

2024-08-06

[Animal modeling - Drug efficacy evaluation] - Tooth pulp stimulation induced pain model

rabbits, weighing 1.5-2kg; Drug: Anesthetic; Equipment: dental drill, platinum electrode, linear ramp function stimulator...

2024-08-06

[Animal modeling - Drug efficacy evaluation] - Chronic pain model induced by electrical stimulation of visceral nerves

rabbits, weighing 2-3kg, male or female not limited; Drug: Anesthetic; Instrument: Electrical stimulator...

2024-08-06

[Animal modeling - efficacy evaluation] - poultry hepatitis B virus model

Duck hepatitis B virus (DHBV) was discovered by William et al in 1980, and then it was found in ducks, grey herons and wild geese from different sources...

2024-08-06

[Animal Modeling Drug Efficacy Evaluation] - Rabbit Chlamydia Pneumonia Model

Take one month old New Zealand rabbits after birth, first anesthetize them with mild halothane to induce hyperventilation, and then inoculate 1.0ml of pure culture medium containing 1.0 × 10000000-5.0 × 10000000 CFU/ml of Chlamydia pneumoniae from th...

2024-08-06