![[Animal Modeling - Pharmacological Evaluation]- Depression Models in Solitary or Separate Care](/./uploads/images/default/default.png)
Some primates or non primates may exhibit characteristic symptoms such as agitation, sleep disorders, and lamenting after separation from their offspring...
2024-08-05![[Animal Modeling Drug Efficacy Evaluation ]- Heymann Nephritis Model in Rats](/./uploads/images/default/default.png)
rats, weighing 150-200g; Drug: Complete Freund\'s adjuvant, physiological saline...
2024-08-05![[Animal Modeling - Pharmacological Evaluation] - Ovarian Resection Induced Osteoporosis Animal Model](/./uploads/images/default/default.png)
Primary osteoporosis includes postmenopausal osteoporosis and senile osteoporosis, mainly characterized by decreased bone mass, degeneration of bone microstructure, decreased bone strength and increased fragility, and susceptibility to fractures...
2024-08-02![[Animal Modeling - Pharmacological Evaluation] - Corticosteroid Induced Osteoporosis Animal Model](/./uploads/images/default/default.png)
The extensive use of glucocorticoids can cause calcium and phosphorus metabolism disorders in animal bodies, reduce the transformation of pre osteoblasts into functional osteoblasts, directly inhibit osteoblast function, reduce collagen synthesis, re...
2024-08-02![[Animal Modeling - Pharmacological Evaluation] - Allogeneic Bone Tumor Animal Model](/./uploads/images/default/default.png)
Allogeneic transplantation refers to the transplantation of the same or homologous animal species. The commonality between the donor and recipient is significant, making it easy to stay in the body, grow and reproduce, and reproduce the tumor process...
2024-08-02
Eye hypersensitivity is mainly a type I hypersensitivity reaction mediated by mast cells. Hay fever conjunctivitis, vernal keratoconjunctivitis, atopic keratoconjunctivitis, and macromastic keratoconjunctivitis are mainly involved in type I allergic ...
2024-08-02![[Animal Modeling - Pharmacological Evaluation] - Corneal Injury Animal Model](/./uploads/images/default/default.png)
Corneal injury can be divided into damage to the corneal endothelium and damage to the corneal epithelium and stroma according to different levels...
2024-08-02![[Animal Modeling - Efficacy Evaluation] - Dry Eye Disease Animal Model](/./uploads/images/default/default.png)
Dry eye disease, also known as dry keratoconjunctivitis, is one of the most common eye diseases, which can cause damage to the ocular surface and blurred vision, affecting the quality of life of patients...
2024-08-02![[Animal Modeling - Pharmacological Evaluation ]- Metabolic Cataract Animal Model](/./uploads/images/default/default.png)
This type of cataract model forms cataracts by affecting the substance metabolism of the crystalline lens through various drugs, commonly used including D-galactose, sodium selenate, naphthalene, and glucocorticoids, as well as less commonly used dru...
2024-08-02![[Animal Modeling - Pharmacological Evaluation] - Chronic Epilepsy Animal Model](/./uploads/images/default/default.png)
The chronic epilepsy model can reflect the initiation, development, and accompanying pathological and physiological changes in the brain during epileptic seizures. This provides a foundation for further research on epilepsy. According to the intensit...
2024-08-02![[Animal Modeling - Pharmacological Evaluation] - Animal Model of Viral Keratitis](/./uploads/images/default/default.png)
The most common viral keratitis is herpes simplex virus keratitis. HSK is a blinding eye disease caused by herpes simplex virus infection, which seriously endangers patients\' visual function. Its clinical characteristics are mainly characterized by ...
2024-08-02
The occurrence of obesity is the result of energy metabolism disorders in the body, and its exact pathogenesis is not fully understood. Currently, it is believed to be related to genetics, central nervous system abnormalities, endocrine dysfunction, ...
2024-08-02![[Animal Modeling - Efficacy Evaluation] - Choline free Ethylthionine Feed Induced Animal Model](/./uploads/images/default/default.png)
In 1975, Lomobardi et al. established a female mouse model of acute hemorrhagic necrotizing pancreatitis by feeding a choline deficient diet supplemented with ethionine...
2024-08-02![[Animal Modeling Drug Efficacy Evaluation] - Traditional Induced Hepatitis B Virus Animal Model](/./uploads/images/default/default.png)
At present, animal models of hepatitis B virus mainly include tree shrew hepatitis B model, duck hepatitis B model, marmot hepatitis B model, and mouse hepatitis B model...
2024-08-02![[Animal Modeling Drug Efficacy Evaluation] - Hepatitis E Virus Rhesus Monkey Model](/./uploads/images/default/default.png)
Hepatitis E is mainly transmitted through the fecal oral route (digestive tract), while other routes include blood transmission and vertical transmission...
2024-08-02![[Animal modeling - efficacy evaluation] - Gene modified pancreatic cancer animal model](/./uploads/images/default/default.png)
In the process of early diagnosis and treatment of pancreatic cancer, it is found that the precancerous lesions of pancreatic cancer, pancreatic intraductal epithelioma, molecular genetic abnormalities, are directly related to pancreatic cancer...
2024-08-02