【Animal Modeling - Pharmacological Evaluation】 - Mouse Bacterial Bronchopneumonia Model

Kunming mice, weighing 21-25g; Drug: Klebsiella pneumoniae strain, hydrocortisone, cyclophosphamide for injection...

2024-07-31

[Animal modeling - Drug efficacy evaluation] - Bacterial infection induced chronic obstructive pulmonary disease rat model

Animal: Clean grade Wistar rats, weighing 185-220g, male or female not limited; Drug: Klebsiella pneumoniae (6 ± 10 ^ 8 CFU/ml)...

2024-07-31

[Animal Modeling - Pharmacological Evaluation] - Early Acute Respiratory Distress Syndrome Animal Model

New Zealand purebred white rabbit, male or female, weighing (1.75 ± 0.25) kg; Medications: Ketamine, Lipopolysaccharide...

2024-07-31

[Animal Modeling - Pharmacological Evaluation] - Pingyangmycin induced Lung Injury Model in Rats

Healthy SD rats, male or female, weighing (210 ± 23) g; Drug: Pingyangmycin, physiological saline; Instrument: Syringe...

2024-07-31

[Animal modeling - Drug efficacy evaluation] - Hemorrhagic shock rat lung injury model

Adult Wistar rats, male, weighing 230-270g; Medications: pentobarbital, physiological saline, heparin, lactate Ringer\'s solution; Equipment: Syringes, surgical instruments, electric blankets, micro infusion pumps, multi-channel physiological recorde...

2024-07-31

【Animal Modeling Drug Efficacy Evaluation】 - Elderly Mouse Acute Lung Injury Model

24 month old Wistar rats, male or female, weighing (456.5 ± 38.1) g; Medications: oleic acid, lipopolysaccharide O111:B4, ketamine...

2024-07-31

[Animal Modeling Drug Efficacy Evaluation]- Rat Liver Transplant Anti Host Rejection Model

The graft-versus-host reaction is a rejection reaction that occurs when lymphocytes in the transplant recognize host antigens, become sensitized, proliferate and differentiate, and directly or indirectly attack the target tissue of the recipient...

2024-07-30

[Animal modeling - Drug efficacy evaluation ]- Method for replicating tumor models

There are many methods to replicate animal tumors, such as irradiating experimental animals with radiation or injecting radioactive isotopes intravenously or locally; Using various chemical carcinogens (alkylating agents, polycyclic aromatic hydrocar...

2024-07-30

[Animal Modeling - Efficacy Evaluation] - Spontaneous Vitiligo Animal Model

Some animals (such as chickens, rodents, dogs, cats, and horses) can be artificially induced to experience local depigmentation. These animals often have anti melanocyte antibodies in their bodies, with the most commonly used being Smyth line (SL) ch...

2024-07-30

[Animal Modeling - Efficacy Evaluation] - Hepatitis A Virus Tree Shrew Model

Take the stool of a hepatitis A patient with positive hepatitis A antigen, prepare a 5% suspension, and centrifuge at 3000 and 8000 rpm for 30 minutes respectively. The supernatant is frozen at -80 ℃ for later use. Adult healthy tree shrews were oral...

2024-07-30

[Animal Modeling - Pharmacological Evaluation] - Mouse Focal Cerebral Ischemia Model

Healthy male 2nd grade Kunming mice, weighing 12-22g; Medications: Pentobarbital, 2,3,5-triphenyltetrazolium chloride...

2024-07-30

【Animal Modeling - Pharmacological Evaluation】 - Canine Acute Myocardial Ischemia Model

Healthy hybrid dogs, each weighing between 15-20 kg; Medications: Ketamine, Sodium Barbital; Equipment: BL-420 biological function experimental system, animal artificial ventilator...

2024-07-29

[Animal modeling - Drug efficacy evaluation] - Verapamil induced bradycardia model

mice, weighing 25-40g, both male and female; Medication: 10% urinary ester, verapamil...

2024-07-29

[Animal Modeling Drug Efficacy Evaluation ]- Rat Uveitis Model Induced by Salmonella Toxins

　　SD rats, grade 2, 6-8 weeks old, weighing 150-180g, male. The endotoxin used was Salmonella typhi endotoxin (LPS, Sigma). The endotoxin was dissolved in sterile physiological saline at a concentration of 2g/L. 50 μ l of endotoxin was injected into ...

2024-07-29

[Animal Modeling Drug Efficacy Evaluation] - Spinal cord or white matter homogenate as antigen induces EAE model

Female Wistar rats, 6-8 weeks old, weighing 130-200g; Guinea pig, female, weighing 330-400g. Reagents. BCG freeze-dried powder, pertussis vaccine, complete Freund\'s adjuvant. Before using the complete Freund\'s adjuvant, add the freeze-dried powder ...

2024-07-29

【Animal Modeling - Pharmacological Evaluation 】- High Fat Feed Induced Hyperlipidemia Animal Model in Rabbits

rabbits, male or female not limited; Medication: High fat feed...

2024-07-29