[Animal Modeling] Drug Efficacy Evaluation Autoimmune Active Activation Model

The earliest research was on PV: Dsg3 deficient mice were immunized by intraperitoneal injection of recombinant mouse Dsg3 and adjuvant. After 32 days of the first immunization, 1 × 10 7th power lymphocytes were taken from the spleen of the mice and ...

2024-07-25

[Animal Modeling - Pharmacological Evaluation] - Oxazolidone Colitis Mouse Model

BALB/c mice, 7-8 weeks old, weighing 25-30g; Medications: Oxazolidone, Metoclopramide, Ethanol...

2024-07-25

[Animal Modeling Drug Efficacy Evaluation] - Rat Mycoplasma Pneumonia Model

Wistar rats, half male and half female, with an average weight of 60g, 3 weeks old; Drug: Mycoplasma pneumoniae liquid, ether; Instrument: Syringe....

2024-07-25

[Animal modeling - Drug efficacy evaluation] - Hemorrhagic shock rat lung injury model

Adult Wistar rats, male, weighing 230-270g; Medications: pentobarbital, physiological saline, heparin, lactate Ringer\'s solution; Equipment: Syringes, surgical instruments, electric blankets, micro infusion pumps, multi-channel physiological recorde...

2024-07-25

[Animal modeling - Drug efficacy evaluation] - Papain induced pulmonary heart disease model

rabbit; Medication: 5% papain solution, wild lily alkaline aqueous solution; Instrument: Nebulizer...

2024-07-25

[Animal modeling - Drug efficacy evaluation] - Surgical induced pulmonary heart disease model

dogs or rabbits; Drug: Anesthetic...

2024-07-25

[Animal Modeling Drug Efficacy Evaluation ]- Rat Pneumocystis Pneumonia Model

Wistar rats, weighing 120-150g; Medications: cortisone acetate, tetracycline...

2024-07-25

[Animal Modeling Drug Efficacy Evaluation] - Animal Model of Pneumococcal Infection after Splenotomy

Wistar rats, male or female, weighing 115g-125g; Drug: Type III pneumococcal; Instrument: Ultrasonic atomizer...

2024-07-25

[Animal Modeling - Pharmacological Evaluation] - Rat Pulmonary Oxidative Injury Model

3-month-old male SD rats; Equipment: O3 generator, dynamic poisoning box...

2024-07-25

[Animal Modeling Drug Efficacy Evaluation] - Elderly Mouse Acute Lung Injury Model

24 month old Wistar rats, male or female, weighing (456.5 ± 38.1) g; Medications: oleic acid, lipopolysaccharide O111:B4, ketamine...

2024-07-25

[Animal Modeling - Pharmacological Evaluation] - Macquarine Induced Myocardial Ischemia Model

healthy dogs, weighing 10-20kg; Medications: Pentobarbital, ergometrine...

2024-07-24

[Animal modeling - Drug efficacy evaluation] - Myocardial infarction model induced by ligating the anterior descending coronary artery in dogs

dogs, weighing over 10kg; Medications: pentobarbital, physiological saline, lidocaine; Equipment: Animal artificial ventilator...

2024-07-24

[Animal Modeling - Efficacy Evaluation] - Babesia jirovecii Infection Animal Model

Babesia belongs to the class of moths, also known as pear pulp worms. Its transmission medium is ticks. There are several genera of pyrophore parasites in warm blooded experimental animals...

2024-07-24

[Animal Modeling - Pharmacological Evaluation] - Animal Model of Postoperative Metastasis of Human Tumors

It is difficult to establish a subcutaneous transplant tumor metastasis model mainly because the tumor is implanted subcutaneously, and its microenvironment is not conducive to the expression of malignant tumor biological characteristics, especially ...

2024-07-24

[Animal Modeling - Pharmacological Evaluation] - In Situ Transplant Tumor Metastasis Animal Model

The metastasis of tumors often has organ specificity rather than random distribution. Some tumor cells have a special tendency to metastasize to certain specific organs. For example, gastric or colorectal cancer usually metastasizes to the liver, and...

2024-07-24

[Animal modeling - Drug efficacy evaluation] - Anesthetic induced bradycardia model

Adult mice weighing 25-40g; Drug: 10% urinary ester; Equipment: Biological function experimental system...

2024-07-24