[Animal modeling - Drug efficacy evaluation] - Verapamil induced bradycardia model

mice, weighing 25-40g, both male and female; Medication: 10% urinary ester, verapamil...

2024-07-29

[Animal Modeling Drug Efficacy Evaluation ]- Rat Uveitis Model Induced by Salmonella Toxins

　　SD rats, grade 2, 6-8 weeks old, weighing 150-180g, male. The endotoxin used was Salmonella typhi endotoxin (LPS, Sigma). The endotoxin was dissolved in sterile physiological saline at a concentration of 2g/L. 50 μ l of endotoxin was injected into ...

2024-07-29

[Animal Modeling Drug Efficacy Evaluation] - Spinal cord or white matter homogenate as antigen induces EAE model

Female Wistar rats, 6-8 weeks old, weighing 130-200g; Guinea pig, female, weighing 330-400g. Reagents. BCG freeze-dried powder, pertussis vaccine, complete Freund\'s adjuvant. Before using the complete Freund\'s adjuvant, add the freeze-dried powder ...

2024-07-29

【Animal Modeling - Pharmacological Evaluation 】- High Fat Feed Induced Hyperlipidemia Animal Model in Rabbits

rabbits, male or female not limited; Medication: High fat feed...

2024-07-29

[Animal Modeling - Pharmacological Evaluation] - Preparation of Cerebral Ischemia Model in Rats with Autologous Thrombosis Combined with Thread Thrombosis Blocking the Middle Cerebral Artery

SD rats, 2-3 months old, half male and half female, with an average weight of (300 ± 50) g; Medications: Chloral hydrate, thrombin...

2024-07-29

[Animal modeling - Drug efficacy evaluation ]- Preparation of influenza virus infection secondary pneumococcal pneumonia model

In the ranking of human disease mortality rates, bacterial pneumonia and influenza rank sixth. Animal models can be used to study the mechanism of interaction between influenza and pneumococcal bacteria...

2024-07-29

[Animal Modeling - Pharmacological Evaluation] - In vivo Thrombosis Animal Model

Wistar rats, male or female, weighing 200-250g; Medications: Ethyl carbamate, heparin injection; Equipment: Disposable intravenous catheter, BL-420 biological function experimental system...

2024-07-29

[Animal Modeling - Pharmacological Evaluation] - Coronary Artery Quantitative Stenosis and Blood Stasis Syndrome Animal Model

Adult experimental dogs were anesthetized and underwent positive pressure artificial respiration with endotracheal intubation. The fifth rib of the left chest was incised, a heart bag was cut, and a pericardial bed was made. The coronary artery was s...

2024-07-29

[Animal Modeling - Pharmacological Evaluation] - Low Selenium Mouse Model of Viral myocarditis

Selenium was discovered over 180 years ago, initially for its toxic effects on the liver. Later, it was found that selenium is essential for the growth of animals and humans at low concentrations, and toxic at high concentrations...

2024-07-29

Animal Modeling Drug Efficacy Evaluation Reflux Gastritis Model

Male rats weighing 200-250g; Medications: Pentobarbital, physiological saline, iodine...

2024-07-29

Animal Modeling Drug Efficacy Evaluation Autoimmune Antibody Passive Transport Model

IgG was taken from patients with bullous pemphigoid (BP) and injected into the cornea of New Zealand rabbits. After 24 hours, epidermal separation, thickening, and blister formation appeared on the cornea. The inflammatory response is dose-dependent,...

2024-07-29

[Animal modeling - Drug efficacy evaluation] - Dry knot constipation model

Healthy Kunming mice, weighing (30 ± 2) g, both male and female...

2024-07-29

[Animal Modeling - Pharmacological Evaluation] - Comprehensive Stimulation Method of Wind Cold and Sulfur Dioxide for Lung Qi Deficiency Animal Model

Adult rats were stimulated with sulfur dioxide at a dose of (200-250) × 10 ^ -5, for 1 hour per day for 13 days. Wind cold stimulation was performed using cold air at a temperature 5 ℃ lower than the living environment temperature of the rats for 15 ...

2024-07-29

[Animal Modeling Drug Efficacy Evaluation ]- Severe Combined Immunodeficiency Mouse Chronic Colitis Model

Female BALB/c mice (H-2 gene phenotype), aged 8-10 weeks at the time of use; Reagents and antibodies: hamster anti mouse CD3 monoclonal antibody, fluorescein isothiocyanate (FITC) labeled anti mouse CD45RB monoclonal antibody, phycoerythrin (PE) labe...

2024-07-29

[Animal Modeling Drug Efficacy Evaluation] - Establishment of Rat Ulcerative Colitis Model by Immune Compound Method

Healthy Wistar rats, half male and half female, weighing approximately 200g; Healthy rabbits; Drug: Complete Freund\'s adjuvant, formaldehyde solution...

2024-07-29

[Animal Modeling Drug Efficacy Evaluation] - Animal Model of Hyperthyroidism with Kidney Yin Deficiency Syndrome

Adult rats were orally administered thyroid hormone at a dose of 2.5mg/kg body weight per day for 3 weeks. The changes in body weight, water intake, urine output, pain threshold, heart rate, etc. before and after modeling were routinely measured. At ...

2024-07-29