![[Animal Modeling Pharmacodynamic Evaluation] - Mouse Tuberculosis Model](/./uploads/images/default/default.png)
Animal models were made by injecting physiological saline into the tail vein, containing 1-5mg/ml of highly toxic human tuberculosis bacteria (H37RV), 0.2ml per animal...
2024-06-27![[Animal modeling - Pharmacodynamic evaluation] - Dynamic lung injury model in chronic pressure overload rats](/./uploads/images/default/default.png)
sham surgery group: Except for not using silk thread to ligate the abdominal aorta, all other steps were the same as the surgery group; Operation group: the model of pressure overload myocardial hypertrophy was prepared according to the abdominal aor...
2024-06-27
The dog underwent thoracotomy under general anesthesia, and the descending aorta was anastomosed with the left pulmonary artery, with a anastomotic opening of less than 1cm. The use of aortic pressure resulted in simple pulmonary hypertension. Alte...
2024-06-27
To study whether pine pollen has synergistic and attenuating effects on cyclophosphamide chemotherapy...
2024-06-26
To provide reference for the selection of experimental animals in liver research by comparing the histomorphological similarity between the livers of four commonly used experimental animals, mice, rats, guinea pigs, and rabbits, and human livers...
2024-06-26
To investigate the role and mechanism of miR-221 in hydrogen peroxide (H2O2)-induced rat cardiomyocyte (H9c2) injury...
2024-06-26
To screen and compare the establishment of a rat model of ovarian hyperstimulation syndrome (OHSS), and to provide a good animal model for the study of the mechanism of OHSS and the development of therapeutic drugs...
2024-06-26
To observe the changes of insulin sensitivity in the liver and peripheral tissues of type 2 diabetic rats at different times after RYGB and to preliminarily explore the possible mechanism...
2024-06-26
To observe the effects of natural enemy sounds on anxiety-like behaviors of SD rats under different durations and repeated stress...
2024-06-26![[Animal modeling] - Study on the safety and effectiveness of human umbilical cord mesenchymal stem cells in the treatment of acute lung injury in mice](/./uploads/images/default/default.png)
To investigate the safety and efficacy of human umbilical cord mesenchymal stem cells (HUC MSCs) in the treatment of lipopolysaccharide (LPS) - induced acute lung injury in mice...
2024-06-26
To investigate the effect of hydrogen-rich solution on the apoptosis of hippocampal neurons and the expression of PI3K/Akt/FoxO1 signaling pathway induced by cerebral ischemia-reperfusion in rats...
2024-06-24![[Animal modeling] - The role of villin 1 in the model of unilateral nephrectomy Habu nephritis in mice](/./uploads/images/default/default.png)
To investigate the similarities and differences between unilateral nephrectomy (UNX) mouse Habu nephritis model and normal mouse Habu nephritis model in renal function, renal pathology and expression of glomerular villin 1 (VIL 1) and their molecular...
2024-06-24![[Animal Modeling - Pharmacodynamic Evaluation] - Spontaneous Vitiligo Animal Model](/./uploads/images/default/default.png)
Humans can induce local depigmentation in some animals, such as chickens, rodents, dogs, cats, and horses. These animals often have anti melanocyte antibodies in their bodies, with the most commonly used being Smyth line (SL) chickens and C57BL mice...
2024-06-19
Inoculating human SCC tissue or cancer cells into the back, forelimb armpits, inguinal area, lateral chest wall, or sublingual area of immunodeficient mice can produce SCC locally...
2024-06-19![[Animal modeling - Pharmacodynamic evaluation] - Gene modified squamous cell carcinoma model](/./uploads/images/default/default.png)
Numerous genes are involved in the pathogenesis of SCC, and gene modified animal models with high or no expression of specific genes can spontaneously or externally induce SCC...
2024-06-19
Ultraviolet (UV) in nature is divided into UVA (315-400nm), UVB (280-315nm), and UVC (100-280nm). The atmospheric ozone can absorb UV with a wavelength less than 280nm, and what enters the ground are UVB and UVA. The most sensitive UV wavelength of t...
2024-06-19