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![[Animal modeling - Pharmacodynamic evaluation] - Preparation of chronic myeloid leukemia animal model using virus transfection method](/./uploads/images/default/default.png)
Chronic myeloid leukemia (CML) is a type of malignant tumor that involves bone marrow hematopoietic stem cells. Ph chromosome or bcr/Abl positivity is a molecular genetic characteristic of CML patients. Therefore, using a reverse transcription virus ...
2024-06-19The animals in the 60mg/kg modeling group were injected subcutaneously under the scapula, or injected intraperitoneally with a 60mg/kg solution of wild lily alkaloids...
2024-06-19The animals in the modeling group were injected with 3% ferric chloride solution via the rabbit ear vein, starting at 0.5ml each time, three times a week, and gradually increasing to four times, with a total injection of 45-60ml. During the injection...
2024-06-19Primary hypogonadism is defined as ovarian insufficiency with high serum follicle-stimulating hormone (FSH) levels. In women, one of the most common forms of primary hypogonadism is premature ovarian failure (POF), also known as premature menopause...
2024-06-18This paper reports an improved method for the isolation of rat thoracic aortic vascular smooth muscle cells based on compound enzymatic digestion...
2024-06-18To study the expression of REST in corticosterone model mice and the effect of REST expression on depression and anxiety behavior in mice, and to explore its role in the mouse model of depression...
2024-06-18To investigate the renal protective effect and mechanism of safflower yellow on streptozotocin-induced diabetic nephropathy in mice...
2024-06-18To construct a mouse model of humanized immune system and transplant it into human prostate cancer cell lines, so as to be used for the research of prostate cancer immunotherapy drugs...
2024-06-18To observe the protective effect of GDF11 on myocardial injury in C57BL/6J mice with type Ⅱ diabetes mellitus and the changes of myocardial apoptosis...
2024-06-18To study the correlation between vascular calcification and serum bone metabolism markers in chronic kidney disease rats...
2024-06-17To explore the role of endoplasmic reticulum protein SEL1L in maintaining normal physiological activities of mammalian central nervous system...
2024-06-17To investigate the effect of rhubarb root extract on the morphology of tissues and organs in experimental psoriasis model mice...
2024-06-17The delayed response test based on the Wisconsin Universal Tester is a common method to evaluate the learning and memory ability of non-human primates. The experiment is affected by many factors during the process. The learning and memory ability has...
2024-06-17To study the toxicity of oral administration of different extracts of Psoralen to rats, and provide a safety basis for its clinical application...
2024-06-17To explore the curative effect of Shenling Baizhu Powder on dextran sulfate sodium (DSS)-induced ulcerative colitis model mice...
2024-06-17To study the effect of minocycline on the hyperpolarization-activated current (Ih) of colloidal (SG) neurons in the spinal dorsal horn of rats...
2024-06-17