【Animal modeling】-Establishment and application of immunocomb detection method for simian immunodeficiency virus antibody

To prepare the SIV30 protein of simian immunodeficiency virus (SIV) by genetic engineering technology as an antigen diagnostic reagent, and to establish an immunocomb method (IC) for the specific detection of anti-SIV antibody IgG in the serum of exp...

2024-07-01

【Animal Modeling】-Pathological Study of Spontaneous Hepatobiliary Hyperplasia in Aged Rats

To accumulate valuable research data on rat hepatic bile duct hyperplasia for related scientific research and new drug safety evaluation...

2024-07-01

【Animal Modeling】-Immune mechanism of systemic lupus erythematosus MRL/lpr mice

To investigate the immune mechanism of MRL/lpr mice with systemic lupus erythematosus at different months of age, and to provide a basis for the study of its pathogenesis...

2024-07-01

【Animal Modeling】-Establishment of basic data of embryo-fetal developmental toxicity test in Bama miniature pigs

To detect the reproductive function indicators and fetal developmental indicators of the embryo-fetal developmental toxicity test in Bama miniature pigs, and to provide reference data for the developmental toxicity study of Bama miniature pigs...

2024-07-01

【Animal Modeling】-Effect of SEL1L gene deletion in central neurons on mouse behavior

To explore the role of endoplasmic reticulum protein SEL1L in maintaining normal physiological activities of mammalian central nervous system...

2024-07-01

[Animal modeling] - Inhibitory effect of cytomegalovirus on some immune indexes of mice implanted with polymethylmethacrylate

To study the inhibitory effect of cytomegalovirus (CMV) on immune response of mice implanted with polymethyl methacrylate (PMMA)...

2024-07-01

【Animal Modeling】-The damage characteristics of olfactory working memory in the very early stage of Alzheimer\\

To investigate the characteristics of olfactory working memory impairment in the very early stage of Alzheimer\\\'s disease transgenic mice...

2024-07-01

【Animal modeling】-Polymorphism analysis of PPARγ2 gene promoter in Wuzhishan miniature pigs

To analyze the polymorphisms in the regulatory region of the PPARγ2 gene promoter in Wuzhishan miniature pigs...

2024-06-28

【Animal Modeling】-Establishment and rapid detection of an animal model of immunocompromised mice

To quickly establish an animal model of KM mice with low immunity, and use a simple and rapid method to identify the establishment of the animal model...

2024-06-28

【Animal Modeling】-Study on changes in the number and traits of cardiac fibroblasts in early postnatal mice

Cardiac fibroblasts account for more than 50% of cardiac cells and play an important role in cardiac physiology and pathology...

2024-06-28

【Animal Modeling】-CBA/CaJ Mice Organ Weight, Blood Physiological and Biochemical Indexes and Immune Cell Proportion

To determine the basic biological indicators of SPF CBA/CaJ mice, and to lay a foundation for better use of this strain of mice for biomedical research...

2024-06-27

【Animal Modeling - Pharmacodynamic Evaluation】- Guinea Pig Tuberculosis Model

Subcutaneous injection of 0.1mg of bacteria into the armpit or chest of the modeling animal...

2024-06-27

[Animal Modeling Pharmacodynamic Evaluation] - Mouse Tuberculosis Model

Animal models were made by injecting physiological saline into the tail vein, containing 1-5mg/ml of highly toxic human tuberculosis bacteria (H37RV), 0.2ml per animal...

2024-06-27

[Animal modeling - Pharmacodynamic evaluation] - Dynamic lung injury model in chronic pressure overload rats

sham surgery group: Except for not using silk thread to ligate the abdominal aorta, all other steps were the same as the surgery group; Operation group: the model of pressure overload myocardial hypertrophy was prepared according to the abdominal aor...

2024-06-27

【Animal modeling - Pharmacodynamic evaluation】 - Surgical induced pulmonary heart disease model

　　The dog underwent thoracotomy under general anesthesia, and the descending aorta was anastomosed with the left pulmonary artery, with a anastomotic opening of less than 1cm. The use of aortic pressure resulted in simple pulmonary hypertension. Alte...

2024-06-27

【Animal modeling】-Study on the synergistic and detoxification effect of pine pollen on cyclophosphamide

To study whether pine pollen has synergistic and attenuating effects on cyclophosphamide chemotherapy...

2024-06-26