[Animal modeling] - High fat diet induced hyperlipidemia animal model in rats

SD or Wistar rats, regardless of gender, weighing 260-280g; Medication: High fat feed...

2024-01-29

【Animal modeling】 - Experimental study on transesophageal low-energy synchronous direct current shock induced atrial fibrillation in animals

Transesophageal atrial pacing is a non-invasive, safe, and simple method for treating paroxysmal supraventricular tachycardia and atrial flutter, but it is ineffective for atrial fibrillation (Af). This article explores the feasibility and efficacy o...

2024-01-29

【Animal modeling】-Protective effect of piperphentonamine hydrochloride on gentamicin-induced hearing loss in guinea pigs

To observe the relationship between the expression of autophagy-related proteins beclin1 and LC3, Na+-K+-2Cl- co-transporter (NKCC1) mRNA, endothelin (ET) and cochlear gentamicin (GM) injury in guinea pig cochlea and piperphentonamine hydrochloride (...

2024-01-27

【Animal Modeling】-The effect of experimental intervention of physiological saline on the caecal microflora and short-chain fatty acid content of broilers

To study the effect of physiological saline intervention on the intestinal flora and short-chain fatty acid content of broiler chickens, to provide specific basis for early microbial intervention experimental research?...

2024-01-27

【Animal modeling】-In vivo biological properties of the porous composite HAPw/n-ZnO implanted in the back muscles of tree shrew

To preliminarily investigate the in vivo biological properties of the porous composite HAPw/n-ZnO...

2024-01-27

【Animal Modeling】-NOD2 promotes the production of nitrosamine by diethyl nitrosamine to study the mechanism of inducing liver tissue inflammation in mice

To investigate the role and mechanism of NOD2, a pattern recognition receptor in hepatocytes, in the process of hepatic inflammation...

2024-01-27

【Animal Modeling】-Electric Cautery and Freezing Method of Myocardial Infarction Animal Model

Similar to thoracotomy, the difference between electrocautery coronary arteries and ligation is that electrocoagulation will cause coronary artery occlusion and local myocardial tissue necrosis due to electric current, leading to myocardial infarctio...

2024-01-27

【Animal Modeling】-Effect of week age on the effect of in vitro fertilization in mice with non-obese diabetic background

To improve the effect of in vitro fertilization in mice with non-obese diabetic background...

2024-01-27

【Animal modeling】-Experimental observation of IFN-γ release from whole blood of rhesus monkeys based on Mycobacterium bovis PPD

To analyze the application value of whole blood IFN-γ release test in the detection of Mycobacterium macaque...

2024-01-27

[Animal modeling] - Establishment of mechanical cardiopulmonary resuscitation model in rats

To explore a feasible method of replicating cardiopulmonary resuscitation (CPR) model in rats by mechanical chest compression...

2024-01-27

[Animal Modeling] - High molecular weight dextran blood stasis syndrome animal model

Adult rabbits were injected with 10% dextran (400000 molecular weight) via ear vein at a dose of 6ml/kg body weight, twice a day for 2 consecutive days. 15 minutes after the last dose, cardiac blood was collected to detect whole blood viscosity, plas...

2024-01-26

[Animal modeling] - Animal model of myocardial infarction and blood stasis syndrome caused by coronary artery ligation

Adult dogs were anesthetized and subjected to tracheal intubation for artificial respiration. The chest was opened in the fourth intercostal space on the left edge of the sternum, exposing the heart and sewing a pericardial bed. After stabilizing for...

2024-01-26

[Animal Modeling] - Experimental Immune Liver Fibrosis Model Induced by Human Serum Albumin

Wistar rats, female, weighing 120-150g; Medications: Human serum albumin, Freund\'s incomplete adjuvant, prostaglandin E1...

2024-01-26

[Animal modeling] - Based on autophagy, explore the effect of fentanyl combined with propofol on myocardial ischemia-reperfusion injury in rats

To investigate the effect of fentanyl combined with propofol on myocardial ischemia-reperfusion injury in rats based on autophagy...

2024-01-26

[Animal modeling] - Establishment of systemic infection model by oral infection of ICR mice with Candida albicans

To establish a systemic infection model by oral infection of ICR mice with C. albicans, and observe the tissue proliferation and distribution of C. albicans in mice after mucosal infection...

2024-01-26

【Animal Modeling】-Observation of the role of endoplasmic reticulum stress-mitochondrial autophagy pathway in pulmonary hypertension in rats

To inhibit endoplasmic reticulum stress in a rat model of pulmonary arterial hypertension induced by monocrotaline, and to observe the role of endoplasmic reticulum stress-mitochondrial pathway in pulmonary arterial hypertension in rats...

2024-01-26