【Animal modeling】-Intervention effect of chitosan on PM2.5-induced acute lung injury in mice

To investigate the intervention effect of chitosan on PM2.5-induced acute lung injury in mice...

2023-12-04

【Animal modeling】-Construct a rat COPD-OSAHS overlap syndrome model by smoking and intermittent hypoxia

To construct a rat model of COPD-OSAHS overlap syndrome, and to provide a feasible means and experimental platform for basic research on OS...

2023-12-04

[Animal modeling] Establishment of cough variant asthma model in Brown Norway rats

To establish a simple and practical animal model of cough variant asthma in Brown\\\'s Norway (BN) rats sensitized with ovalbumin (OVA)...

2023-12-04

[Animal modeling] - Study on coagulation function of rat sepsis model

To investigate the changes of coagulation function in sepsis rat model induced by cecal ligation and puncture...

2023-12-04

[Animal modeling] - Establishment and evaluation of a mouse model of endogenous infection induced by intestinal dissemination

To establish a mouse model of endogenous infection induced by intestinal dissemination, so as to provide a reliable experimental model for studying the mechanism of intestinal microecology and endogenous infection...

2023-12-04

【Animal Modeling】-Effect of subchronic exposure to diflubenzuron on the blood system of rats

Based on the study of the subchronic oral toxicity of diflubenzuron to rats, the effect on the blood system of rats after exposure was preliminarily discussed...

2023-12-04

[Animal modeling] - Study on the relationship between the tree shrew gallstone model and substance P in the digestive tract

To investigate the relationship between the establishment of tree shrew gallstone model by feeding tree shrews with high cholesterol diet and substance P...

2023-12-02

【Animal Modeling】-Expression of Thrombomodulin in Rat Model of Deep Vein Thrombosis and Its Significance

To observe the expression and significance of thrombomodulin in the natural evolution process of deep vein thrombosis and regression in rats...

2023-12-02

【Animal modeling】-Effect of knockout TRPC6 on MPTP-induced neuroinflammatory injury in mice

To detect the expression of TRPC6 channel in microglia in a mouse MPTP-induced neuroinflammation model, and to explore the effect of TRPC6 channel on inflammatory expression and dopaminergic neuron damage...

2023-12-02

[Animal modeling] - Establishment of Bama miniature pig hypertension model induced by high-fat and high-salt diet and its mechanism

To establish the hypertension model of Bama miniature pig with high-fat and high-salt diet and explore its possible pathogenesis...

2023-12-02

[Animal modeling] Establishment of rat model of myocardial cell mitochondrial damage induced by bupivacaine

To observe the morphological changes of mitochondria and the production of reactive oxygen species (ROS) in cardiac myocytes induced by electric stimulation of bupivacaine, and to establish an ideal model of rat cardiac myocytes poisoned by bupivacai...

2023-12-02

[Animal modeling] - Study on the control and optimization of rat oral ulcer animal model by chemical burning method

To establish an animal model of oral ulcer in SD rats by different chemical burning methods and screen the best scheme for the evaluation of therapeutic effect...

2023-12-02

[Animal modeling] Screening of differentially expressed genes and functional analysis in APP/PS1 Alzheimer\\

To analyze the differentially expressed genes in the prefrontal cortex of Alzheimer\\\'s disease (AD) model mice and reveal the pathogenesis of AD from the transcriptome level...

2023-12-02

【Animal Modeling】-Biosafety and Data Quality Considerations for Animal Experiments on Highly Infectious Drugs in ABSL-3 Facility

Animal models are the key to the study of serious infectious diseases, and are of great significance to determine the pathogenesis of the disease and develop vaccines and drugs...

2023-11-30

[Animal modeling] - Pancreatic kallidinogenase alleviates oxidative stress and fibrosis in rats with myocardial ischemia-reperfusion injury

To investigate the effects of pancreatic kallidinogenase on myocardial injury, oxidative stress and fibrosis in rats with myocardial ischemia reperfusion injury...

2023-11-30

【Animal Modeling】 - Establishing Humans α A Parkinson\'s disease rat model with synaptic nuclear protein A30P mutation

Founder α⁃ Parkinson\\\\\\\'s disease model of transgenic rats with synaptonuclein A30P mutant...

2023-11-30