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【Animal modeling】-Subacute inhalation toxicity study of ivermectin original drug in rats

【Animal modeling】-Subacute inhalation toxicity study of ivermectin original drug in rats

To study the subacute inhalation toxicity of ivermectin original drug to rats, and to find the maximum ineffective dose...

2024-10-14
[Animal Modeling] - Sterile Pericarditis Model

[Animal Modeling] - Sterile Pericarditis Model

Atrial fibrillation often occurs after thoracotomy, and pericarditis is considered an important cause of atrial fibrillation...

2024-10-11
[Animal Modeling] - Exploration of Evaluation Methods for Rat Models of Phlegm Dampness Stagnation Syndrome in Premature Sexual Maturity

[Animal Modeling] - Exploration of Evaluation Methods for Rat Models of Phlegm Dampness Stagnation Syndrome in Premature Sexual Maturity

To explore a systematic evaluation method for a rat model of precocious puberty with phlegm dampness obstruction syndrome...

2024-10-11
[Animal modeling] - The changes of dendritic cell function in white haired black eye rabbit allergic rhinitis model mediated by ovalbumin

[Animal modeling] - The changes of dendritic cell function in white haired black eye rabbit allergic rhinitis model mediated by ovalbumin

To observe the function of dendritic cells derived from peripheral blood of white haired black eyed rabbits and Japanese white rabbits with allergic rhinitis induced by ovalbumin, and to reveal the possible mechanism of WHBE rabbits\\\\\\\' sensitivi...

2024-10-08
【 Animal Modeling 】 - Optimization of modeling method for primary liver cancer in mice

【 Animal Modeling 】 - Optimization of modeling method for primary liver cancer in mice

To establish a good, fast, and stable mouse primary liver cancer model...

2024-10-08
【Animal Modeling】-How to establish an ELISA detection method for mouse anti-rabies virus IgG antibody

【Animal Modeling】-How to establish an ELISA detection method for mouse anti-rabies virus IgG antibody

How to establish a mouse anti-rabies virus IgG antibody ELISA detection method for the detection and analysis of rabies mouse models?...

2024-10-08
【Animal modeling】-The role of mitochondria-cytochrome C pathway in the apoptosis of rabbit non-alcoholic fatty liver hepatocytes

【Animal modeling】-The role of mitochondria-cytochrome C pathway in the apoptosis of rabbit non-alcoholic fatty liver hepatocytes

To investigate the role of mitochondria-cytochrome C pathway in the apoptosis of rabbit non-alcoholic fatty liver liver cells...

2024-10-08
[Animal modeling] - identification of a skin type lupus mouse model

[Animal modeling] - identification of a skin type lupus mouse model

To observe and identify the skin symptoms of aged systemic lupus erythematosus (TC) mice and explore whether it can be used as a mouse model for studying cutaneous lupus...

2024-10-07
[Animal Modeling] - The Improving Effect of Sulindac on Symptomatic Behavior in Autism Model Rats

[Animal Modeling] - The Improving Effect of Sulindac on Symptomatic Behavior in Autism Model Rats

To explore the improvement effect of sulindac on the behavior of autism model rats...

2024-10-07
Animal modeling drug efficacy evaluation disseminated intravascular coagulation

Animal modeling drug efficacy evaluation disseminated intravascular coagulation

New Zealand rabbit, weighing around 2.5kg. Inject 10ml of standard crude E. coli endotoxin (containing 5 × 10 of E. coli per milliliter to the 7th power) intravenously, followed by 10ml intravenously after 6-24h. After the second injection, diffuse i...

2024-09-27
【Animal modeling - Drug efficacy evaluation】 - Cryotherapy combined with resection method induced chronic renal failure rat model

【Animal modeling - Drug efficacy evaluation】 - Cryotherapy combined with resection method induced chronic renal failure rat model

Anesthetize animals with 30mg/kg pentobarbital, disinfect the skin routinely, make an incision on the left side of the abdomen, expose the left side, and peel off the renal fascia. Freeze the upper, lower, lateral anterior, and posterior parts of the...

2024-09-27
[Animal Modeling - Efficacy Evaluation] - Transgenic Mouse Infection Model

[Animal Modeling - Efficacy Evaluation] - Transgenic Mouse Infection Model

Cut the fragment containing HCV 5\'UTR and structural genes (C1+E1+E2) from the pHCS plasmid by enzymatic digestion, pass it through the intermediate vector pMT, and then perform enzymatic digestion to construct a new plasmid (pCBE). After amplificat...

2024-09-26
[Animal Modeling - Pharmacological Evaluation] - Chronic Renal Failure Rat Model Induced by Xiaozhiling

[Animal Modeling - Pharmacological Evaluation] - Chronic Renal Failure Rat Model Induced by Xiaozhiling

Model animals are first anesthetized with ketamine and diazepam, supplemented with ether inhalation if necessary. Rats were fixed in a supine position, and a 1.2ml dilution of refined Xiaozhiling injection was prepared by adding an equal amount of ph...

2024-09-26
【Animal Modeling - Pharmacological Evaluation】 - Adenosine induced Chronic Renal Failure Rat Model

【Animal Modeling - Pharmacological Evaluation】 - Adenosine induced Chronic Renal Failure Rat Model

1ml of adenine suspension was prepared at a daily dose of 200mg/kg and administered to rats by gavage at regular intervals, with a total cumulative dose of 1.5g/animal. The entire modeling process lasted for 24 days. Administer once a day from day 1 ...

2024-09-26
[Animal modeling - Drug efficacy evaluation] - Negative pressure traumatic brain injury model

[Animal modeling - Drug efficacy evaluation] - Negative pressure traumatic brain injury model

The negative pressure traumatic brain injury model established by Mahmood et al. mainly consists of a stent, straw, syringe tube, spring coil, pressure sensing transducer, oscilloscope, etc...

2024-09-25
[Animal Modeling - Efficacy Evaluation] - Hepatitis B Virus Infection Model

[Animal Modeling - Efficacy Evaluation] - Hepatitis B Virus Infection Model

Hepatitis B virus belongs to the hepatotropic DNA virus, which is a complex DNA virus. Since the 1970s, researchers have identified Dane particles (i.e. HBV particles) under electron microscopy and clarified that the surface component of HBV particle...

2024-09-25