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【Animal modeling】-Lipopolysaccharide-induced knee joint fibroblast-like synovial cell inflammation model in SD rats and analysis of its characteristics

【Animal modeling】-Lipopolysaccharide-induced knee joint fibroblast-like synovial cell inflammation model in SD rats and analysis of its characteristics

To establish a primary culture method of normal knee synovial cells in (SD) rats and a lipopolysaccharide-induced fibroblast-like synovial cell inflammation model...

2024-10-23
[Animal Modeling] - Gene Modified Heart Failure Model

[Animal Modeling] - Gene Modified Heart Failure Model

Adult mice exhibit hemodynamic and clinical signs similar to human HF. Therefore, using gene knockout or transgenic mouse models to alter the expression of heart specific genes, and studying the roles and mechanisms of certain genes in cardiac develo...

2024-10-23
【Animal modeling】-Prokaryotic expression of monkey D-type retrovirus p27 gene and establishment of flow immunofluorescence microsphere detection technology

【Animal modeling】-Prokaryotic expression of monkey D-type retrovirus p27 gene and establishment of flow immunofluorescence microsphere detection technology

To construct the p27 protein of simian D-type retrovirus, and establish a flow immunofluorescence microsphere detection technology for the detection of simian D-type retrovirus...

2024-10-22
[Animal Modeling] - Comparative Study on Hepatotoxicity of Matrine and Oxymatrine in Vivo and in Vitro Models

[Animal Modeling] - Comparative Study on Hepatotoxicity of Matrine and Oxymatrine in Vivo and in Vitro Models

To compare the hepatotoxicity of matrine and oxymatrine, in order to explore their severity and characteristics of toxicity, and to preliminarily elucidate the toxicity mechanism?...

2024-10-22
【Animal modeling】-Exploration of the protective effect of bifidobacteria on liver function in rats with chronic alcoholic liver injury

【Animal modeling】-Exploration of the protective effect of bifidobacteria on liver function in rats with chronic alcoholic liver injury

To investigate the protective or influence of bifidobacteria on liver function in rats with chronic alcoholic liver injury, and to explore its mechanism preliminarily...

2024-10-22
[Animal Modeling]- Progress in Establishment and Application of Leukemia Mouse Models

[Animal Modeling]- Progress in Establishment and Application of Leukemia Mouse Models

Leukemia, also known as \\\"blood cancer\\\", is characterized by the malignant and unrestricted proliferation of leukemia cells in the bone marrow and other hematopoietic tissues, infiltrating various tissues and organs throughout the body...

2024-10-22
[Animal modeling] Protective effect of siraitin V on rats with meconium aspiration syndrome and its preliminary mechanism

[Animal modeling] Protective effect of siraitin V on rats with meconium aspiration syndrome and its preliminary mechanism

To observe the protective effect of momordica grosvenorii saponin V on acute lung injury in rats with meconium aspiration syndrome (MAS) and explore its mechanism...

2024-10-21
【Animal Modeling】-partial simple epilepsy model in rats

【Animal Modeling】-partial simple epilepsy model in rats

1. Model animals: male or female rats weighing 200-300 g: drugs: pentobarbital, FeCl3 solution, equipment: rat stereotaxic device....

2024-10-21
【Animal Modeling】-improved New Zealand Rabbit Common Carotid Artery Cannulation Fixation Method

【Animal Modeling】-improved New Zealand Rabbit Common Carotid Artery Cannulation Fixation Method

To investigate a stable, not easy to fall off, and continuous and timed blood collection method for the common carotid artery cannulation of New Zealand rabbits...

2024-10-21
【Animal modeling】-Effect of telmisartan on the expression of PPARs and adiponectin receptor 2 in liver tissue of rats with non-alcoholic fatty liver disease

【Animal modeling】-Effect of telmisartan on the expression of PPARs and adiponectin receptor 2 in liver tissue of rats with non-alcoholic fatty liver disease

To investigate the effect of telmisartan on the expression of PPARs and adiponectin receptor 2 in liver tissue of rats with non-alcoholic fatty liver disease...

2024-10-21
【Animal modeling】-Effect of camel milk on glucose and lipid metabolism and PPAR-γ, TNF-α mRNA in type 2 diabetic rats

【Animal modeling】-Effect of camel milk on glucose and lipid metabolism and PPAR-γ, TNF-α mRNA in type 2 diabetic rats

To study the effect of camel milk (CM) on body weight, blood glucose, blood lipid, insulin, PPARγ and TNF-α gene expression in type 2 diabetic rats...

2024-10-21
[Animal modeling]- establishment of a gastric cancer metastasis model based on clinical tumor specimens

[Animal modeling]- establishment of a gastric cancer metastasis model based on clinical tumor specimens

To establish a gastric cancer metastasis model based on clinical tumor specimens and provide personalized animal models for the study of gastric cancer metastasis...

2024-10-21
【Animal modeling】-Characteristics of liver pathological damage in db/db mice with spontaneous type 2 diabetes

【Animal modeling】-Characteristics of liver pathological damage in db/db mice with spontaneous type 2 diabetes

To dynamically observe the pathological changes and characteristics of the liver of db/db mice with spontaneous type 2 diabetes mellitus, and to provide the basic theory and experimental basis for the experimental study of using the liver of db/db mi...

2024-10-15
[Animal Modeling] - Elderly Kidney Yang Deficiency Animal Model

[Animal Modeling] - Elderly Kidney Yang Deficiency Animal Model

24 month old rats, detecting adrenal cortex 3 β- Hydroxysterol dehydrogenase (3 β- HSD, Testicular Enzyme...

2024-10-15
[Animal Modeling ]- Animal Model of Kidney Yang Deficiency Syndrome in Atrial Labor Injury

[Animal Modeling ]- Animal Model of Kidney Yang Deficiency Syndrome in Atrial Labor Injury

Male mice were selected as the modeling objects, and healthy estrous female mice were used to induce \\\"atrioventricular dysregulation\\\"...

2024-10-14
[Animal modeling] - Establishment of a rat model of coronary heart disease with Qi deficiency and blood stasis syndrome

[Animal modeling] - Establishment of a rat model of coronary heart disease with Qi deficiency and blood stasis syndrome

To explore the modeling method of CHD model with syndrome of Qi deficiency and blood stasis by analyzing the pathology, etiology, tongue manifestation of the compound model and the relationship with prostacyclin and thromboxane A2...

2024-10-14