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[Animal Modeling] Drug Efficacy Evaluation Induced Psoriasis Animal Model

[Animal Modeling] Drug Efficacy Evaluation Induced Psoriasis Animal Model

Propranolol application induced ear psoriasis model in guinea pigs. This model is commonly used in China. Huang et al. applied 5% propranolol to the ear of guinea pigs (350-400g) and the ear of guinea pigs (0.3g per 1cm2 of drug) twice a day for two...

2024-07-22
[Animal Modeling] Drug Efficacy Evaluation Reflux Gastritis Model

[Animal Modeling] Drug Efficacy Evaluation Reflux Gastritis Model

Male rats weighing 200-250g; Medications: Pentobarbital, physiological saline, iodine...

2024-07-22
[Animal Modeling - Pharmacological Evaluation] - Animal Model of Spleen Qi Deficiency Syndrome Caused by Bitter Cold Diarrhea (Rhubarb)

[Animal Modeling - Pharmacological Evaluation] - Animal Model of Spleen Qi Deficiency Syndrome Caused by Bitter Cold Diarrhea (Rhubarb)

Adult mice were orally administered with a dose of 0.2ml/10g body weight of raw rhubarb solution (1g of raw medicine per milliliter) twice a day for 7 consecutive days. Observe changes in mouse food intake, stool, activity, fur, body weight, etc. Aft...

2024-07-22
[Animal modeling - Drug efficacy evaluation] - Dry knot constipation model

[Animal modeling - Drug efficacy evaluation] - Dry knot constipation model

Healthy Kunming mice, weighing (30 ± 2) g, both male and female...

2024-07-22
【Animal Modeling - Pharmacological Evaluation 】- Oxazolidone Colitis Mouse Model

【Animal Modeling - Pharmacological Evaluation 】- Oxazolidone Colitis Mouse Model

BALB/c mice, 7-8 weeks old, weighing 25-30g; Medications: Oxazolidone, Metoclopramide, Ethanol...

2024-07-22
[Animal Modeling Drug Efficacy Evaluation] - Small Pig Renal Artery Stenosis Hypertension Model

[Animal Modeling Drug Efficacy Evaluation] - Small Pig Renal Artery Stenosis Hypertension Model

In addition to the DOCA hypertensive miniature pig model, experimental renal artery stenosis can also lead to the formation of renal hypertension...

2024-07-18
[Animal Modeling - Pharmacological Evaluation] - Small Pig Root Absorption Model

[Animal Modeling - Pharmacological Evaluation] - Small Pig Root Absorption Model

Root resorption is a common and difficult complication in orthodontic treatment. There are many factors that can cause root resorption, including age, gender, nutritional status, type of orthodontic appliance, magnitude of orthodontic force, orthodon...

2024-07-18
[Animal Modeling - Pharmacological Evaluation] - Experimental Induced Intervertebral Disc Prolapse Animal Model

[Animal Modeling - Pharmacological Evaluation] - Experimental Induced Intervertebral Disc Prolapse Animal Model

Through the intervention of external experimental methods, the load-bearing capacity of the intervertebral disc undergoes sustained changes, overload, physical damage, or destruction of the normal anatomical structure of the intervertebral disc, lead...

2024-07-18
[Animal Modeling - Pharmacological Evaluation] - Heterogeneic Animal In Situ Transplantation Bone Tumor Model

[Animal Modeling - Pharmacological Evaluation] - Heterogeneic Animal In Situ Transplantation Bone Tumor Model

Usually, tumor blocks or cells are implanted subcutaneously in nude mice, and the tumor continues to grow, simulating the process of human malignant tumor formation. The tumor formation rate is high, the tumor formation time is uniform, the tumor siz...

2024-07-18
[Animal Modeling Drug Efficacy Evaluation] - T-cell Transplantation Psoriasis Animal Model

[Animal Modeling Drug Efficacy Evaluation] - T-cell Transplantation Psoriasis Animal Model

Although the specific pathogenesis of psoriasis is not fully understood, the role of T lymphocytes in it is increasingly supported by evidence...

2024-07-18
[Animal Modeling - Pharmacological Evaluation] - Chemical Induced Brain Tumor Model

[Animal Modeling - Pharmacological Evaluation] - Chemical Induced Brain Tumor Model

Injecting some chemical carcinogens into different parts of animals in different ways can induce tumors, but the incidence, type, and location of tumors induced by carcinogens vary depending on their dosage, animal age, strain, and physiological stat...

2024-07-18
[Animal Modeling - Pharmacological Evaluation] - Corneal Injury Animal Model

[Animal Modeling - Pharmacological Evaluation] - Corneal Injury Animal Model

Corneal injury can be divided into damage to the corneal endothelium and damage to the corneal epithelium and stroma according to different levels...

2024-07-18
[Animal Modeling - Pharmacological Evaluation] - Corneal Neovascularization Animal Model

[Animal Modeling - Pharmacological Evaluation] - Corneal Neovascularization Animal Model

Corneal neovascularization often leads to a decrease in corneal transparency, which is an important cause of blindness and a high-risk factor for rejection reactions after corneal transplantation...

2024-07-18
[Animal Modeling - Efficacy Evaluation] - Dry Eye Disease Animal Model

[Animal Modeling - Efficacy Evaluation] - Dry Eye Disease Animal Model

Dry eye disease, also known as dry keratoconjunctivitis, is one of the most common eye diseases, which can cause damage to the ocular surface and blurred vision, affecting the quality of life of patients...

2024-07-18
[Animal Modeling - Pharmacological Evaluation ]- Animal Model of Retinal Disease Caused by Light Damage

[Animal Modeling - Pharmacological Evaluation ]- Animal Model of Retinal Disease Caused by Light Damage

At present, it is believed that retinal damage caused by strong light or continuous light exposure is influenced by species, region, diet, pre-treatment of light feeding history, and genetic background. One of the mechanisms of retinal oxidative ligh...

2024-07-18
[Animal Modeling - Pharmacological Evaluation]- Inducing Retinal Pigmentation Degeneration Animal Model

[Animal Modeling - Pharmacological Evaluation]- Inducing Retinal Pigmentation Degeneration Animal Model

Inducing retinal diseases involves the use of drugs or physical methods to alter the structure of the retina, resulting in conditions similar to human retinitis pigmentosa...

2024-07-18