[Animal Modeling - Pharmacological Evaluation] - Evaporation induced Mouse Dry Eye Model

Dysfunction of meibomian gland and strong evaporation type rabbit dry eye model. Some special types of mice already have factors of meibomian gland developmental disorders...

2024-08-07

[Animal modeling - efficacy evaluation] - DB/DB obese diabetes mice

Diabetes mice: It was first reported by Hummel et al. (1966) that it was caused by a recessive mutation gene and spontaneously originated from inbred mice (C57BL/Ks) in Jackson\'s laboratory. This gene (db) and obesity (ob) are not alleles, but locat...

2024-08-06

[Animal modeling - Drug efficacy evaluation] - Tooth pulp stimulation induced pain model

rabbits, weighing 1.5-2kg; Drug: Anesthetic; Equipment: dental drill, platinum electrode, linear ramp function stimulator...

2024-08-06

[Animal modeling - Drug efficacy evaluation] - Chronic pain model induced by electrical stimulation of visceral nerves

rabbits, weighing 2-3kg, male or female not limited; Drug: Anesthetic; Instrument: Electrical stimulator...

2024-08-06

[Animal modeling - efficacy evaluation] - poultry hepatitis B virus model

Duck hepatitis B virus (DHBV) was discovered by William et al in 1980, and then it was found in ducks, grey herons and wild geese from different sources...

2024-08-06

[Animal Modeling Drug Efficacy Evaluation] - Rabbit Chlamydia Pneumonia Model

Take one month old New Zealand rabbits after birth, first anesthetize them with mild halothane to induce hyperventilation, and then inoculate 1.0ml of pure culture medium containing 1.0 × 10000000-5.0 × 10000000 CFU/ml of Chlamydia pneumoniae from th...

2024-08-06

[Animal Modeling Drug Efficacy Evaluation] - Guinea Pig Pulmonary Tuberculosis Bacterial Model

Female Hartley guinea pigs were used. Mycobacterium tuberculosis in the middle logarithmic growth period was diluted to the required inoculation concentration with sterilized double distilled water. The compartment of the spray was filled with 5ml of...

2024-08-06

【Animal modeling - Drug efficacy evaluation】 - Repeated immunization induced ulcerative colitis in rats

Wistar rats, female, weighing (180 ± 10) g; Medications: pentobarbital, penicillin; Equipment: body locator, electronic stimulator...

2024-08-06

[Animal Modeling Drug Efficacy Evaluation] - Staphylococcus aureus Endometritis Animal Model

Cultivate Staphylococcus aureus ATCC29213 strain and prepare a bacterial suspension of 10000 CFU/ml using physiological saline...

2024-08-06

[Animal modeling - Drug efficacy evaluation]- Establishment of post-traumatic epilepsy animal model by iontophoresis method

Animal: Wistar rats, male, weighing 200-250g; Medication: pentobarbital, FeCl3 solution; Instruments: rat stereotaxic apparatus, wireless Bluetooth EEG monitoring system, high-speed dental drill, tooth holder powder, 1 PVC thin tube with an inner dia...

2024-08-06

[Animal Modeling Drug Efficacy Evaluation] - Rat Pseudomonas aeruginosa Pneumonia Model

Secretory Pseudomonas aeruginosa PAO1 strain and its variant PAOR strain were cultured overnight in tryptone soy broth at 37 ° C. After centrifugation, they were suspended in PBS (pH 7.4), washed by centrifugation, and the precipitate was suspended i...

2024-08-06

[[Animal modeling - efficacy evaluation] - primary diabetes BB rats

BB Wistar rat is a spontaneous diabetes animal model...

2024-08-06

[Animal Modeling - Efficacy Evaluation] - Mongolian Sand Rat Helicobacter pylori Model

5-week-old male Mongolian sand rats without specific pathogen grade were fed standard feed and sterilized water with libitum...

2024-08-06

[Animal Modeling - Pharmacological Evaluation] - Penicillin induced Epilepsy Animal Model

SD rats, half male and half female, weighing (300 ± 20) g; Drug: Penicillin...

2024-08-06

[Animal Modeling Drug Efficacy Evaluation] - Rabbit Pseudomonas aeruginosa Pneumonia Model

Select a small amount of mucinous PA colonies stored at 4 ℃, incubate them in MH broth at 37 ℃ for 24 hours, and prepare a bacterial suspension of 0.5 units using MH broth. Freshly prepare on the same day of use. New Zealand rabbits aged from 18 to 2...

2024-08-06

【Animal modeling - Drug efficacy evaluation】 - Cortical injection of ferrous chloride to establish a traumatic epilepsy animal model

Healthy adult male SD rats weighing 180-220g; Drug: 10% chloral hydrate, FeCl2 solution...

2024-08-06