Language
![[Animal Modeling Drug Efficacy Evaluation] - Rhesus Monkey HGV Infection Model](/./uploads/images/default/default.png)
Experimental rhesus monkeys weighing 2.5-6.5kg and aged 2-8 years were selected. Prior to infection, ALT enzyme activity was detected to be normal, and liver biopsy showed no dynamic liver pathological changes...
2024-08-05Wistar rats, weighing (216 ± 10) g; Instrument: Electroconvulsive device...
2024-08-05mouse; Drug: a mixture of 96.2% N2 and 3.8% O2 gas, pure CO2, NaNO2; Instrument: a sealed jar...
2024-08-05Dilute the foot-and-mouth disease virus ORMF8 with 0.01mol/L PBS (pH 7.4) to an LD50 of 10-3 to 10-7/0.2ml, and then inject each titer of virus solution intradermally through the hind limb toes of guinea pigs, with an injection dose of 0.2ml per anim...
2024-08-05Tree shrews were inoculated via femoral vein with 0.5ml of serum from hepatitis B patients with positive hepatitis B B virus surface antigen (HBsAg) and hepatitis B B virus e antigen (HBeAg)...
2024-08-05Select adult Japanese large eared rabbits and inject a 1% mass fraction of ferric chloride aqueous solution into the rabbit ear vein. Inject 0.5ml twice a week from week 1 to week 4; From the 5th to the 6th week, twice a week, 0.75ml each time; In th...
2024-08-05Some primates or non primates may exhibit characteristic symptoms such as agitation, sleep disorders, and lamenting after separation from their offspring...
2024-08-05rats, weighing 150-200g; Drug: Complete Freund\'s adjuvant, physiological saline...
2024-08-05Primary osteoporosis includes postmenopausal osteoporosis and senile osteoporosis, mainly characterized by decreased bone mass, degeneration of bone microstructure, decreased bone strength and increased fragility, and susceptibility to fractures...
2024-08-02The extensive use of glucocorticoids can cause calcium and phosphorus metabolism disorders in animal bodies, reduce the transformation of pre osteoblasts into functional osteoblasts, directly inhibit osteoblast function, reduce collagen synthesis, re...
2024-08-02Allogeneic transplantation refers to the transplantation of the same or homologous animal species. The commonality between the donor and recipient is significant, making it easy to stay in the body, grow and reproduce, and reproduce the tumor process...
2024-08-02Eye hypersensitivity is mainly a type I hypersensitivity reaction mediated by mast cells. Hay fever conjunctivitis, vernal keratoconjunctivitis, atopic keratoconjunctivitis, and macromastic keratoconjunctivitis are mainly involved in type I allergic ...
2024-08-02Corneal injury can be divided into damage to the corneal endothelium and damage to the corneal epithelium and stroma according to different levels...
2024-08-02Dry eye disease, also known as dry keratoconjunctivitis, is one of the most common eye diseases, which can cause damage to the ocular surface and blurred vision, affecting the quality of life of patients...
2024-08-02This type of cataract model forms cataracts by affecting the substance metabolism of the crystalline lens through various drugs, commonly used including D-galactose, sodium selenate, naphthalene, and glucocorticoids, as well as less commonly used dru...
2024-08-02The chronic epilepsy model can reflect the initiation, development, and accompanying pathological and physiological changes in the brain during epileptic seizures. This provides a foundation for further research on epilepsy. According to the intensit...
2024-08-02